1.1.1.132: GDP-mannose 6-dehydrogenase
This is an abbreviated version!
For detailed information about GDP-mannose 6-dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.132
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1.1.1.132
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aeruginosa
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alginate
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cystic
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fibrosis
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mucoid
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mannuronic
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midecamycin
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sputum
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vinelandii
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molecular-genetic
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azotobacter
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erythromycin
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macrolide
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elastase
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chemoenzymatic
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gdpmannose
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multidrug-resistant
- 1.1.1.132
- aeruginosa
- alginate
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cystic
- fibrosis
- mucoid
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mannuronic
- midecamycin
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sputum
- vinelandii
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molecular-genetic
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azotobacter
- erythromycin
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macrolide
- elastase
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chemoenzymatic
- gdpmannose
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multidrug-resistant
Reaction
Synonyms
algD, GDP mannose dehydrogenase, GDP-D-mannose dehydrogenase, GDP-mannose dehydrogenase, GMD, GMD1, GMD2, guanosine diphosphate mannose dehydrogenase, guanosine diphospho-D-mannose dehydrogenase, guanosine diphosphomannose dehydrogenase
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Organism
Organism on EC 1.1.1.132 - GDP-mannose 6-dehydrogenase
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NCIB 8789, water soluble polysaccharide producing strains E, W and O
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SM52B, mutant of A. vinelandii NCIB 9068, alginate-prducing ability, no activity with sorbitol as sole carbon source during batch growth, enzyme not produced, loss of ability to synthesise alginate during prolonged continuous culture after 300 h for mutant and more than 1000 h for parent strain, ability transferable by conjugation
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algD gene overproduced in strain 8822 using a plasmid vector containing algD under control of the tac promoter
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enzyme overproduced using 3 different plasmid vectors containing algD under control of the tac promoter expressed in non-mucoid strain PAO1 and mucoid strain PAO568, pPT3 and pPT4 are forward and reverse clones contain leader sequence with possible transcriptional/translational regulatory sequences of algD gene, no significant activity with pMMB66EH and pPT4 in either IPTG induced or non induced Escherichia coli, mucoid and non-mucoid Pseudomonas aeruginosa strains
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enzyme overproduced using a plasmid vector containing algD under control of the tac promoter
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mucoid clinical isolate PT-1578 and non-mucoid PAO1, very low activity of PAO1 regardless whether using nutrient-rich or poor medium, low activity with PT-1578 on enriched, increased on nutritionally poor medium
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mucoid strains of cystic fibrosis patients 8821 and its high-alginate-producing spontaneously variant 8821M, enzyme overproduced using 2 different plasmid vectors containing algD under control of the tac promoter mobilized into both strains
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mucoid strains of cystic fibrosis patients 8821, its high-alginate-producing spontaneously variant 8821M, IST23, IST27 and IST30, mucoid strains derived from the spontaneous nonmucoid strains during prolonged incubation under nutrient limitation in acetamide broth (Nm), rich in PolyP, no activity in spontaneous swiched nonmucoid variants (N) of initial isolated mucoid strains
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overexpression of tac promoter controlled algD gene containing different plasmids in mucoid strains FRD1 and PAO568 and non-mucoid strains FRD2 and PAO1
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