1.1.1.159: 7alpha-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 7alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.159

1.1.1.159

chenodeoxycholic

cholic

testosteroni

bacteroides

thin-layer

3alpha-hydroxysteroid

synthesis

fragilis

7alpha-oh

glycochenodeoxycholic

nadp-dependent

ursodeoxycholic

perfringens

degradation

analysis

Reaction

3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate

Synonyms

7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid, J-1-1, NADP(H)-dependent 7alpha-HSDH, NADP(H)-dependent 7alpha-hydroxysteroid dehydrogenase, NADP+-dependent 7alpha-HSDH, nicotinamide adenine dinucleotide phosphate-dependent 7alpha-hydroxysteroid dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.159 7alpha-hydroxysteroid dehydrogenase

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Results	in table
9	Activating Compound
1020	AA Sequence
8	Application
1	CAS Registry Number
13	Cloned(Commentary)
40	Cofactor
4	Crystallization (Commentary)
12	General Information
4	General Stability
37	Inhibitors
13	kcat/KM [mM/s]
61	KM Value [mM]
10	Metals/Ions
16	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
57	Organism
3	Pathway
26	PDB ID
16	pH Optimum
3	pH Range
4	pH Stability
1	pI Value
33	Protein Variants
17	Purification (Commentary)
4	Reaction
3	Reaction Type
45	Reference
2	Source Tissue
31	Specific Activity [micromol/min/mg]
4	Storage Stability
133	Substrates and Products (Substrate)
15	Subunits
38	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
15	Temperature Stability [°C]
24	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.1.1.159 - 7alpha-hydroxysteroid dehydrogenase

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2-mercaptoethanol

Bacteroides fragilis

286078

ascorbic acid