1.1.1.16: galactitol 2-dehydrogenase
This is an abbreviated version!
For detailed information about galactitol 2-dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.16
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1.1.1.16
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dehydrogenases
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polyols
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rhodobacter
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sphaeroides
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xylitol
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l-tagatose
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d-galactose
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diol
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1,2-hexanediol
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ribitol
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nad+-dependent
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s-1,2-propanediol
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his6-tagged
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leloir
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4-dehydrogenase
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synthesis
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l-arabitol
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nidulans
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regioselective
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l-xylulose
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rhizobium
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bioconversion
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hydroxyacetone
- 1.1.1.16
- dehydrogenases
- polyols
-
rhodobacter
- sphaeroides
- xylitol
- l-tagatose
- d-galactose
- diol
- 1,2-hexanediol
- ribitol
-
nad+-dependent
- s-1,2-propanediol
-
his6-tagged
-
leloir
-
4-dehydrogenase
- synthesis
- l-arabitol
- nidulans
-
regioselective
- l-xylulose
- rhizobium
-
bioconversion
- hydroxyacetone
Reaction
Synonyms
dulcitol dehydrogenase, galactitol dehydrogenase, GDH, Lad1, LadB
ECTree
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Application
Application on EC 1.1.1.16 - galactitol 2-dehydrogenase
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synthesis
the enzyme can be used to produce optically pure building blocks and for the bioconversion of bioactive compounds
synthesis
a yeast strain capable of consuming lactose intracellularly is engineered to produce tagatose from lactose. GAL1 coding for galactose kinase is deleted to eliminate galactose utilization. Heterologous xylose reductase (XR) and galactitol dehydrogenase (GDH) are introduced into the Gal1 deletion strain. The expression levels of XR and GDH are adjusted to maximize tagatose production. The resulting engineered yeast produces 37.69 g/l of tagatose from lactose with a tagatose and galactose ratio of 9:1 in the reaction broth
synthesis
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the enzyme can be used to produce optically pure building blocks and for the bioconversion of bioactive compounds
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