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1.1.1.168: 2-dehydropantolactone reductase (Re-specific)

This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase (Re-specific), go to the full flat file.

Word Map on EC 1.1.1.168

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
 +
NADPH
 +
H+

Synonyms

(R)-pantoyl-lactone:NADP+ oxidoreductase (A-specific), 2-dehydropantoyl-lactone reductase, 2-dehydropantoyl-lactone reductase (A-specific), 2-ketopantoyl lactone reductase, AKR, CPR, ketopantoyl lactone reductase, NADPH-dependent aldo-keto reductase, NADPH-dependent conjugated polyketone reductase, reductase, 2-oxopantoyl lactone

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.168 2-dehydropantolactone reductase (Re-specific)

KM Value

KM Value on EC 1.1.1.168 - 2-dehydropantolactone reductase (Re-specific)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0057 - 0.085
1-methylisatin
0.484 - 20.4
2-dehydropantolactone
0.0031
5-bromoisatin
-
-
0.0083 - 0.016
5-methylisatin
0.015
8-bromobornanedione
-
-
0.83
alloxan
-
-
0.093
beta-naphthoquinone
-
-
0.012
bornanedione
-
-
0.42
dihydro-4,4-diethyl-2,3-furanedione
-
-
0.983
dihydro-4-methyl-4-propyl-2,3-furanedione
-
-
0.043
dihydro-5-(2-butyl)-4-methyl-4-ethyl-2,3-furanedione
-
-
0.013
dihydro-5-(2-pentyl)-4,4-dimethyl-2,3-furanedione
-
-
0.09
dihydro-5-(2-pentyl)-4-methyl-4-propyl-2,3-furanedione
-
-
0.0098
dihydro-5-(3-pentyl)-4,4-dimethyl-2,3-furanedione
-
-
0.0093
dihydro-5-isopropyl-4,4-dimethyl-2,3-furanedione
-
-
0.064
dl-camphorquinone
-
-
0.0066 - 0.014
isatin
0.031 - 0.333
ketopantoyl lactone
0.039 - 0.062
NADPH
0.52
ninhydrin
-
-
0.026
oxopantoyl lactone
-
-