1.1.1.206: tropinone reductase I
This is an abbreviated version!
For detailed information about tropinone reductase I, go to the full flat file.
Word Map on EC 1.1.1.206
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1.1.1.206
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tropane
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reductases
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hyoscyamine
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scopolamine
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datura
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pseudotropine
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stramonium
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solanaceae
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calystegines
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putrescine
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n-methyltransferase
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solanaceous
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3-quinuclidinone
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synthesis
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nortropane
- 1.1.1.206
-
tropane
- reductases
- hyoscyamine
- scopolamine
- datura
- pseudotropine
- stramonium
- solanaceae
-
calystegines
- putrescine
- n-methyltransferase
-
solanaceous
- 3-quinuclidinone
- synthesis
-
nortropane
Reaction
Synonyms
BaTRI, dehydrogenase, tropine, DnTR1, DsTRI, EC 1.1.1.293, More, TR-I, TR1, TRI, Tri2, tropine biosynthetic tropinone reductase, Tropine dehydrogenase, tropine-forming reductase, tropine-forming tropinone reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-I, tropinone reductase-I 2, WcTR-I, WsTR-I, WsTR-I protein
ECTree
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Engineering
Engineering on EC 1.1.1.206 - tropinone reductase I
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additional information
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overexpression of tropinone reductases TRI and TRII, EC 1.1.1.236, from Datura stramonium alters alkaloid composition in Atropa belladonna root cultures, overview
additional information
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various mutants: H112Y/A160S, A160S/V168E, V168E/H112Y, H112Y/A160S/V168E, I223L/F226L, H112Y/A160S/V168E/I223L/F226L, all mutants have different Km values for tropinone and NADPH
additional information
overexpression of tropinone reductases TRI and TRII, EC 1.1.1.236, from Datura stramonium alters alkaloid composition in Atropa belladonna root cultures, overview
additional information
enzyme suppression in potato plants by RNA interference (RNAi) and enzyme overexpression. The overexpression and gene knockdown of StTRI alters tropinone reduction in vivo, but has no influence on calystegine accumulation,in contrast to genetic manipulation of isozyme St-TRII, EC 1.1.1.236, phenotypes, calystegine analysis overview. Higher availability of tropinone, when StTRI gene expression is reduced, and enhanced formation of pseudotropine, that may result in a higher calystegine accumulation, are not evident
additional information
-
enzyme suppression in potato plants by RNA interference (RNAi) and enzyme overexpression. The overexpression and gene knockdown of StTRI alters tropinone reduction in vivo, but has no influence on calystegine accumulation,in contrast to genetic manipulation of isozyme St-TRII, EC 1.1.1.236, phenotypes, calystegine analysis overview. Higher availability of tropinone, when StTRI gene expression is reduced, and enhanced formation of pseudotropine, that may result in a higher calystegine accumulation, are not evident