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1.1.1.219: dihydroflavonol 4-reductase

This is an abbreviated version!
For detailed information about dihydroflavonol 4-reductase, go to the full flat file.

Word Map on EC 1.1.1.219

Reaction

a (2R,3S,4S)-leucoanthocyanidin
+
NADP+
=
a (2R,3R)-dihydroflavonol
+
NADPH
+
H+

Synonyms

Bo9g058630, BrDFR1, BrDFR10, BrDFR11, BrDFR12, BrDFR2, BrDFR3, BrDFR4, BrDFR5, BrDFR6, BrDFR7, BrDFR8, BrDFR9, CsDFR, Cyp82C1, cytochrome P450 CYP82C1, DcDFR, DFL1, DFR, DFR1, DFR1a, DFR2, DFR3, DFR4a, DFR4b, DFR5, DgDFR, DHM reductase, DHQ reductase, dihydroflavanol 4-reductase, dihydroflavanol-4-reductase-like protein, dihydroflavonol 4-reductase, dihydroflavonol reductase, dihydroflavonol-4-reductase, dihydrokaempferol 4-reductase, dihydromyricetin reductase, dihydroquercetin reductase, DnDFR, flavan-3-ol NADPH-dihydromycertin reductase, flavonoid 3'-hydroxylase, GbDFR1, GbDFR2, GbDFR3, IbDFR, McDFR, NADPH-dihydromyricetin reductase, NtDFR1, PAS_chr3_0449, PgDFR, PhDFR, reductase, dihydromyricetin, reductase, dihydroquercetin, RrDFR1, TaDFR, TaDFR-A, TaDFR-I, TRANSPARENT TESTA 3 protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.219 dihydroflavonol 4-reductase

Engineering

Engineering on EC 1.1.1.219 - dihydroflavonol 4-reductase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
N141A
mutation modifies the preference of DFRa for dihydroquercetin and dihydromyricetin, and also weakens its stability
N141D
mutation modifies the preference of DFRa for dihydroquercetin and dihydromyricetin, and also weakens its stability
N133D
-
site-directed mutagenesis,
additional information