1.1.1.22: UDP-glucose 6-dehydrogenase

This is an abbreviated version!
For detailed information about UDP-glucose 6-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.22

1.1.1.22

udp-glucuronic

polysaccharide

ugdhs

glycosaminoglycans

hyaluronan

pyrophosphorylase

udp-xylose

glucuronic

glucuronidation

udp-glca

exopolysaccharide

udp-sugars

medicine

glca

udpga

udp-d-glucuronate

udp-glucuronyltransferase

hasas

pharmacology

agriculture

molecular biology

synthesis

Reaction

+ 2 NAD⁺ +

+ 2 NADH + 2 H+

Synonyms

ADH-like UDP-glucose dehydrogenase, AglM, BceC, Cj1441c, dehydrogenase, uridine diphosphoglucose, dual specificity UDP-glucose dehydrogenase, GbUGD, GH_D12G1806, HasB, HasB2, HVO_1531, jekyll m151, kfiD, PA2022, PA3559, PH02Gene21682, sqv-4, Sugarless protein, UDG1, UDP-alpha-D-glucose:NAD oxidoreductase, UDP-D-glucose dehydrogenase, UDP-GDH, UDP-Glc dehydrogenase, UDP-Glc DH, UDP-GlcDH, UDP-GlcDHase, UDP-glucose dehydrogenase, UDPDH, UDPG dehydrogenase, UDPG-DH, UDPG:NAD oxidoreductase, UDPGD, UDPGDH, UDPGDH-A, UDPGDH-B, UDPGlc dehydrogenase, UDPglucose dehydrogenase, UDPglucose:NAD+ oxidoreductase, Ugd, UGD1, Ugd2, UgdG, UGDH, UGDH4, uridine diphosphate D-glucose dehydrogenase, uridine diphosphate glucose dehydrogenase, uridine diphosphate glucose-6-dehydrogenase, uridine diphosphate-glucose dehydrogenase, uridine diphosphoglucose dehydrogenase, uridine-5'-diphosphoglucose dehydrogenase, uridyl phosphate dehydrogenase, VNG1048G, VNG_1048G

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.22 UDP-glucose 6-dehydrogenase

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Results	in table
20	Activating Compound
48190	AA Sequence
14	Application
1	CAS Registry Number
44	Cloned(Commentary)
44	Cofactor
14	Crystallization (Commentary)
64	Disease/ Diagnostics
4	Expression
56	General Information
8	General Stability
65	Inhibitors
8	kcat/KM [mM/s]
15	Ki Value [mM]
127	KM Value [mM]
6	Localization
4	Metals/Ions
50	Molecular Weight [Da]
49	Natural Substrates/ Products (Substrates)
120	Organism
9	Pathway
157	PDB ID
22	pH Optimum
10	pH Range
2	pH Stability
1	pI Value
2	Posttranslational Modification
67	Protein Variants
32	Purification (Commentary)
11	Reaction
2	Reaction Type
110	Reference
64	Source Tissue
23	Specific Activity [micromol/min/mg]
6	Storage Stability
180	Substrates and Products (Substrate)
55	Subunits
141	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
5	Temperature Range [°C]
7	Temperature Stability [°C]
48	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 1.1.1.22 - UDP-glucose 6-dehydrogenase

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17beta-estradiol

Oryctolagus cuniculus

upregulation of UDP-glucose dehydrogenase at mRNA, protein and activity level in articular chondrocyte

690024

3-pyridinealdehyde adenine dinucleotide

can replace NAD+

ADP

slight activation

AMPPNP

ATP

dATP

highly activating

Deamino adenine dinucleotide

2 entries

diphosphate

Escherichia coli

740710

lactose

Streptococcus equi subsp. zooepidemicus

UDP-GlcDH activities in extracts of Lactococcus lactis strain NFHA01 induced with both 0.5% and 2% lactose are significantly higher than that of the same strain without induction. UDP-GlcDH activity of NFHA01 induced with 2% lactose is about 110% higher than that of 0.5% lactose induction

698529

nicotinamide hypoxanthine dinucleotide

Rattus norvegicus

can replace NAD+

286296

nisin

Streptococcus equi subsp. zooepidemicus

induces the expression of szHasA together with szHasB

698529

TGF-beta

Oryctolagus cuniculus

enhances enzyme activity in articular chondrocyte

690024

Thionicotinamide adenine dinucleotide

UDP

slight activation

UTP

best activating nucleotide triphosphate

740710

additional information

2 entries