1.1.1.252: tetrahydroxynaphthalene reductase

This is an abbreviated version!
For detailed information about tetrahydroxynaphthalene reductase, go to the full flat file.

Reaction

Synonyms

1,3,6,8-tetrahydroxynaphthalene reductase, 1,3,8-trihydroxynaphthalene reductase, 3HNR, 4HN, BdsA, EC 1.3.1.50, hydroxynaphthalene reductase, MGG_02252, NADPH-dependent naphthol reductase, naphthol reductase, reductase, naphthol, reductase, naphthol (Magnaporthe grisea clone pAV501 precursor reduced), T4HN reductase, T4HNR, tetrahydroxynaphthalene reductase (Magnaporthe grisea clone pAV501), THNR, trihydroxynaphthalene reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.252 tetrahydroxynaphthalene reductase

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Results	in table
33	AA Sequence
5	Application
2	CAS Registry Number
7	Cloned(Commentary)
18	Cofactor
3	Crystallization (Commentary)
5	General Information
27	IC50 Value
64	Inhibitors
20	Ki Value [mM]
11	KM Value [mM]
3	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
24	Organism
8	PDB ID
4	pH Optimum
2	pH Range
1	Protein Variants
6	Purification (Commentary)
2	Reaction
2	Reaction Type
24	Reference
3	Specific Activity [micromol/min/mg]
1	Storage Stability
82	Substrates and Products (Substrate)
4	Subunits
27	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
4	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.1.1.252 - tetrahydroxynaphthalene reductase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.00058

1-[(Z)-2-bromo-2-nitroethenyl]-3-fluorobenzene

Pyricularia oryzae

Q12634

pH 7.0, 30°C

740164

0.00029

1-[(Z)-2-bromo-2-nitroethenyl]-4-ethylbenzene

Pyricularia oryzae

Q12634

pH 7.0, 30°C

740164

0.025

3,7-dihydroxyflavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.025

3-hydroxyflavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.0058

5,7-dihydroxyflavone

2 entries

0.025

5-hydroxyflavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.025

5-methoxyflavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.023

7,4'-Dihydroxyflavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.0049

acacetin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.0031

apigenin

2 entries

0.012

baicalein

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.012

Biochanin A

2 entries

0.018

chrysoeriol

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.0057

diosmetin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.055

flavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.0079

kaempferol

2 entries

0.0068

luteolin

2 entries

0.026

naringenin

2 entries

0.026

quercetin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.015

scutellarein

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.00023

Tricyclazole

Pyricularia oryzae

Q12634

pH 7.0, 30°C

740164

0.0058

5,7-dihydroxyflavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.0058

5,7-dihydroxyflavone

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.0031

apigenin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.0031

apigenin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.012

Biochanin A

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.012

Biochanin A

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.0079

kaempferol

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.0079

kaempferol

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.0068

luteolin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.0068

luteolin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274

0.026

naringenin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one

697279

0.026

naringenin

Curvularia lunata

-

at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C

697274