1.1.1.265: 3-methylbutanal reductase
This is an abbreviated version!
For detailed information about 3-methylbutanal reductase, go to the full flat file.
Word Map on EC 1.1.1.265
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1.1.1.265
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enantioselectivity
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ketoreductase
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furfural
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lignocellulosic
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5-hydroxymethylfurfural
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glycolaldehyde
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butanoate
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benzaldehyde
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l-carnitine
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aldo-keto
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sporobolomyces
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spycatcher
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desalting
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salmonicolor
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spytag
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1-dehydrogenase
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nutrition
- 1.1.1.265
-
enantioselectivity
- ketoreductase
- furfural
-
lignocellulosic
- 5-hydroxymethylfurfural
- glycolaldehyde
- butanoate
- benzaldehyde
- l-carnitine
-
aldo-keto
-
sporobolomyces
-
spycatcher
-
desalting
- salmonicolor
-
spytag
-
1-dehydrogenase
- nutrition
Reaction
Synonyms
3-methylbutyraldehyde reductase, aldehyde reductase, bcADH, branched-chain alcohol dehydrogenase, Gre2, GRE2 gene product, Gre2p, isoamylaldehyde reductase, isopentanal reductase, isovaleral reductase, isovaleraldehyde reductase, More, protein YIM1, YIM1, YMR152W, Ymr152wp, YOL151W, YOL151w gene product
ECTree
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General Information
General Information on EC 1.1.1.265 - 3-methylbutanal reductase
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evolution
physiological function
in strains lacking Gre2 activity, which are subjected to environmental stress straining the cell membrane, growth is significantly and exclusively reduced. No compensatory mechanisms are activated due to loss of Gre2p during growth in favourable conditions (synthetic defined media, no stress), but a striking and highly specific induction of the ergosterol biosynthesis pathway, enzymes Erg10, Erg19 and Erg6, is observed in Gre2 mutant strains during growth in a stress conditions in which lack of Gre2 significantly affects growth. Mutant strains display vastly impaired tolerance exclusively to agents targeting the ergosterol biosynthesis
phylogenetic analysis indicates that Ymr152wp and selected proteins similar to Ymr152wp are classified into the MDR family, which is close to the QOR subfamily and the LTD subfamily, but is far from the zinc-containing subfamilies of the ADH subfamily, the CADH subfamily, and the YADH subfamily in the genetic tree
evolution
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phylogenetic analysis indicates that Ymr152wp and selected proteins similar to Ymr152wp are classified into the MDR family, which is close to the QOR subfamily and the LTD subfamily, but is far from the zinc-containing subfamilies of the ADH subfamily, the CADH subfamily, and the YADH subfamily in the genetic tree
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