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1.1.1.268: 2-(R)-hydroxypropyl-CoM dehydrogenase

This is an abbreviated version!
For detailed information about 2-(R)-hydroxypropyl-CoM dehydrogenase, go to the full flat file.

Reaction

2-(R)-hydroxypropyl-CoM
+
NAD+
=
2-oxopropyl-CoM
 +
NADH
 +
H+

Synonyms

(R)-hydroxypropyl-coenzyme M dehydrogenase, (R)-hydroxypropylthioethanesulfonate dehydrogenase, 2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase, 2-(R)-hydroxypropyl-coenzyme M dehydrogenase, R-HPCDH, xecD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase

KCat KM Value

KCat KM Value on EC 1.1.1.268 - 2-(R)-hydroxypropyl-CoM dehydrogenase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.003
(2R)-2-butanol
recombinant enzyme, pH and temperature not specified in the publication
-
0.68
(2R)-2-heptanol
recombinant enzyme, pH and temperature not specified in the publication
-
0.59
(2R)-2-hexanol
recombinant enzyme, pH and temperature not specified in the publication
-
262.75
(2R)-2-hydroxypropyl-CoM
recombinant enzyme, pH and temperature not specified in the publication
-
1.57
(2R)-2-octanol
recombinant enzyme, pH and temperature not specified in the publication
-
0.055
(2R)-2-pentanol
recombinant enzyme, pH and temperature not specified in the publication
-
0.007
(2S)-2-butanol
recombinant enzyme, pH and temperature not specified in the publication
-
0.44
(2S)-2-hydroxypropyl-CoM
recombinant enzyme, pH and temperature not specified in the publication
0.019
(2S)-2-pentanol
recombinant enzyme, pH and temperature not specified in the publication
-
8.69
(R)-2-butanol
pH 7.5, 30°C
26.4
(S)-2-butanol
pH 7.5, 30°C
0.39
2-(2-hydroxyethylthio)ethanesulfonate
recombinant enzyme, pH and temperature not specified in the publication
500
2-(R)-hydroxypropyl-CoM
pH 7.5, 30°C
0.53
2-(S)-hydroxypropyl-CoM
pH 7.5, 30°C
420
2-oxopropyl-CoM
pH 7.5, 30°C
0.0017
2-propanol
recombinant enzyme, pH and temperature not specified in the publication