1.1.1.300: NADP-retinol dehydrogenase

This is an abbreviated version!
For detailed information about NADP-retinol dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.300

1.1.1.300

retinoids

photoreceptors

cone

rhodopsin

11-cis-retinal

all-trans-retinoic

leber

retinyl

amaurosis

retinylamine

opsin

medicine

pharmacology

Reaction

Synonyms

aldehyde dehydrogenase, ALDH, all-trans retinal reductase, all-trans-retinaldehyde reductase, all-trans-retinol dehydrogenase, CG2065, CG2070, CG30491, CG3842, DHRS3, EC 5.2.1.3, hRDH5, hRoDH, More, mouse RDH11, mRDH11, NADP(H)-dependent retinol dehydrogenase/reductase, NADP+-dependent all-trans-retinol dehydrogenase, NADPH-dependent retinal reductase, NDRD, NRDR, NRDRA1, NRDRB1, NRDRB2, peroxisomal NADP(H)-dependent retinol dehydrogenase-reductase, photoreceptor retinol dehydrogenase, photoreceptor-associated retinol dehydrogenase, photoreceptor-specific retinol dehydrogenase, prRDH, RalR1, RDH, RDH10, RDH11, Rdh11/12-like 1, Rdh11/12-like 2, Rdh11/12-like 3, RDH12, RDH13, RDH14, RDH8, retinal reductase, retinal reductase 1, retinaldehyde reductase, retinoid dehydrogenase/reductase, retinoid oxidoreductase complex, Retinol dehydrogenase, retinol dehydrogenase 10, retinol dehydrogenase 11, retinol dehydrogenase 12, retinol dehydrogenase 13, retinol dehydrogenase 8, retinol dehydrogenase [NADP+], retinol dehydrogenase-10, retinol dehydrogenases 11-like, retSDR1, RHD8, ROC, SDR16C4, short-chain dehydrogenase/reductase RRD

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.300 NADP-retinol dehydrogenase

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Results	in table
1173	AA Sequence
3	Application
1	CAS Registry Number
30	Cloned(Commentary)
88	Cofactor
1	Crystallization (Commentary)
36	Disease/ Diagnostics
2	Expression
66	General Information
7	Inhibitors
5	kcat/KM [mM/s]
1	Ki Value [mM]
67	KM Value [mM]
30	Localization
8	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
86	Organism
1	Oxidation Stability
2	Pathway
11	PDB ID
3	pH Optimum
2	pI Value
1	Posttranslational Modification
43	Protein Variants
9	Purification (Commentary)
1	Reaction
67	Reference
131	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
112	Substrates and Products (Substrate)
6	Subunits
133	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Stability [°C]
12	Turnover Number [1/s]

KM Value

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KM Value on EC 1.1.1.300 - NADP-retinol dehydrogenase

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0.0001

11-cis-retinal

Homo sapiens

Q96NR8

pH 7.4, 37°C

667674

0.0016

11-cis-retinol

Homo sapiens

Q96NR8

pH 7.4, 37°C

667674

0.62

13-cis-retinal

Homo sapiens

Q8TC12

pH 7.4, 37°C, determined with NADP+

656064

0.00014 - 0.19

9-cis-retinal

2 entries

0.0016

9-cis-retinol

Homo sapiens

Q96NR8

pH 7.4, 37°C

667674

0.0032 - 0.0044

all-trans-3-hydroxyretinal

3 entries

0.00006 - 0.5

all-trans-retinal

19 entries

0.0006 - 1.3

all-trans-retinol

6 entries

0.0096 - 0.0307

estrone

3 entries

0.004 - 680

NAD+

3 entries

2.22 - 1300

NADH

4 entries

0.0004 - 0.8

NADP+

9 entries

0.00047 - 0.23

NADPH

10 entries

0.007 - 0.13

retinal

2 entries

additional information

5 entries