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1.1.1.326: zerumbone synthase

This is an abbreviated version!
For detailed information about zerumbone synthase, go to the full flat file.

Reaction

10-hydroxy-alpha-humulene
+
NAD+
=
zerumbone
+
NADH
+
H+

Synonyms

ZSD1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.326 zerumbone synthase

Cloned

Cloned on EC 1.1.1.326 - zerumbone synthase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene ZSD1, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
gene zsd1, recombinant expression in Saccharomyces cerevisiae strain W303-1a, functional co-expression with alpha-humulene synthase (ZSS1), alpha-humulene 8-hydroxylase (CYP71BA1), and AtCPR1 from Arabidopsis thaliana, subcloning in Escherichia coli