1.1.1.336: UDP-N-acetyl-D-mannosamine dehydrogenase

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For detailed information about UDP-N-acetyl-D-mannosamine dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.336

1.1.1.336

2-epimerase

polysaccharide

pyrococcus

enterobacterial

transposon

udp-n-acetylglucosamine

uridylyltransferase

horikoshii

diagnostics

Reaction

+ 2 NAD⁺ +

+ 2 NADH + 2 H+

Synonyms

MMP0706, UDP-D-ManNAcDH, UDP-ManNAc 6-dehydrogenase, WbpA, wbpA2, wbpA_2, wecC

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.336 UDP-N-acetyl-D-mannosamine dehydrogenase

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Results	in table
4	Activating Compound
5595	AA Sequence
1	Application
4	Cloned(Commentary)
3	Cofactor
2	Crystallization (Commentary)
7	General Information
5	Inhibitors
5	KM Value [mM]
2	Metals/Ions
7	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
52	Organism
6	Pathway
1	pH Optimum
1	Protein Variants
2	Purification (Commentary)
1	Reaction
11	Reference
1	Source Tissue
1	Storage Stability
5	Substrates and Products (Substrate)
6	Subunits
13	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

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General Information on EC 1.1.1.336 - UDP-N-acetyl-D-mannosamine dehydrogenase

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evolution

Edwardsiella tarda

Edwardsiella tarda strains can be grouped into two types of human isolates and diseased fish isolates based on distribution of the wecC gene, type III and type VI secretion system genes, the groups are broadly clustered into two major subpopulations: EdwGI and EdwGII. Edwardsiella tarda EdwGI is composed of strains mainly isolated from fish, such as the turbot, striped bass, and Japanese eel, represents a genotype of fish pathogens, and possesses virulence-associated gene clusters such as T3SS and T6SS. Edwardsiella tarda EdwGII contains strains isolated from human feces, nonpathogenic strains to fish, and environmental strains, and lacks some important virulence-associated gene clusters including T3SS and T6SS

743240

malfunction

Edwardsiella tarda

motility activity, including swarming and swimming, of the wecC mutant is weaker than that f the wild-type strain

743240

metabolism

2 entries

physiological function

3 entries