1.1.1.362: aklaviketone reductase

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For detailed information about aklaviketone reductase, go to the full flat file.

Reaction

Synonyms

DauE

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.362 aklaviketone reductase

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Results	in table
38	AA Sequence
1	Cloned(Commentary)
1	Cofactor
1	General Information
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
7	Pathway
1	Reaction
1	Reference
4	Substrates and Products (Substrate)
1	Subunits
1	Synonyms
1	Systematic Name

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.362 - aklaviketone reductase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

aklaviketone + NADPH + H+

aklavinone + NADP+

Streptomyces sp.

Q53882

the enzyme is involved in the biosynthesis of the anthracyclins aclacinomycin and daunomycin. Aklavinone is the last intermediate common to both aclacinomycin and daunomycin biosynthesis

722491

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