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1.1.1.363: glucose-6-phosphate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about glucose-6-phosphate dehydrogenase [NAD(P)+], go to the full flat file.

Word Map on EC 1.1.1.363

Reaction

D-glucose 6-phosphate
+
NAD(P)+
=
6-phospho-D-glucono-1,5-lactone
+
NAD(P)H
+
H+

Synonyms

G6-PDH, G6PD, G6PDH, G6PDH-1, Glc6PD, Glu-6-PDH, glucose 6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate dehydrogenase Zwf, NADP+- and NAD+-dependent G6PDH, PputG6PDH-1, zwf-1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]

KI Value

KI Value on EC 1.1.1.363 - glucose-6-phosphate dehydrogenase [NAD(P)+]

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.12
2',5'-ADP
-
pH 7.8, 25°C, substrate: NADP+
1.3
2'-AMP
-
pH 7.8, 25°C, substrate: NAD+
2
5'-AMP
-
pH 7.8, 25°C, substrate: NAD+
1
acetyl-CoA
-
24°C, pH 7.8, inhibition of NAD+-dependent reaction
36
adenosine
-
pH 7.8, 25°C, substrate: NAD+
3.1
ADP
-
pH 7.8, 25°C, substrate: NAD+
0.52
ADP-ribose
-
pH 7.8, 25°C, substrate: NAD+
0.3 - 1.5
ATP
0.15
cis-9-octadecenoyl-CoA
-
24°C, pH 7.8, inhibition of NAD+-dependent reaction
0.7
CoA
-
24°C, pH 7.8, inhibition of NAD+-dependent reaction
0.4
malonyl-CoA
-
24°C, pH 7.8, inhibition of NAD+-dependent reaction
95
N'-methylnicotinamide
-
pH 7.8, 25°C, substrate: NAD+
0.76 - 1.3
NAD+
0.00337 - 8.23
NADP+
1.8
NADP+ 2',3'-dialdehyde
-
25°C, pH 7.8
0.006 - 0.163
NADPH
105
nicotinamide
-
pH 7.8, 25°C, substrate: NAD+
0.034 - 0.04
pyridoxal 5'-diphospho-5'-adenosine
0.039
pyridoxal 5'-phosphate
-
25°C, pH 7.7, competitive inhibition when glucose 6-phosphate is varied at a constant, nearly saturating concentration of NAD+
additional information
vanadate
-
inhibition constants with respect to D-glucose 6-phosphate, NAD+ or NADP+