1.1.1.47: glucose 1-dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about glucose 1-dehydrogenase [NAD(P)+], go to the full flat file.

Word Map on EC 1.1.1.47

1.1.1.47

glucocorticoid

glucose-6-phosphate

11beta-hydroxysteroid

cortisone

adipose

corticosterone

11beta-hsd1

hsd11b1

11-dehydrocorticosterone

prereceptor

oxo-reductase

synthesis

biotechnology

energy production

analysis

diagnostics

Reaction

Synonyms

alkali-resistant glucose 1-dehydrogenase, beta-D-glucose:NAD(P)+ 1-oxido-reductase, beta-D-glucose:NAD(P)+ 1-oxidoreductase, BmGlcDH-III, BmGlcDH-IV, bzgdh, D-glucose dehydrogenase (NAD(P)), EC 1.1.5.2, GDH, gdh-2, GDHB, general stress protein 74, GlcDH, GlcDH-I, GlcDH-II, GlcDH-IWG3, glucose 1-dehydrogenase, glucose 1-dehydrogenase 3, glucose 1-dehydrogenase B, glucose 1-dehydrogenase III, glucose 1-dehydrogenase IV, glucose dehydrogenase, glucose1-dehydrogenase, GluDH, GSP74, hexose phosphate dehydrogenase, hexose-6-phosphate dehydrogenase, LsGDH, More, NAD(P)-dependent glucose 1-dehydrogenase, NAD(P)-dependent glucose dehydrogenase, NAD(P)-dependent glucose-1-dehydrogenase, NAD-GDH, nicotinamide adenine dinucleotide (NAD)-linked glucose dehydrogenase, SsGDH, SSO3204

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]

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Results	in table
11	Activating Compound
21836	AA Sequence
31	Application
1	CAS Registry Number
37	Cloned(Commentary)
106	Cofactor
13	Crystallization (Commentary)
134	Disease/ Diagnostics
3	General Information
15	General Stability
66	Inhibitors
48	kcat/KM [mM/s]
3	Ki Value [mM]
271	KM Value [mM]
20	Localization
36	Metals/Ions
70	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
45	Organic Solvent Stability
215	Organism
5	Pathway
79	PDB ID
35	pH Optimum
13	pH Range
34	pH Stability
11	pI Value
2	Posttranslational Modification
100	Protein Variants
39	Purification (Commentary)
6	Reaction
3	Reaction Type
126	Reference
1	Renatured (Commentary)
16	Source Tissue
51	Specific Activity [micromol/min/mg]
14	Storage Stability
349	Substrates and Products (Substrate)
73	Subunits
128	Synonyms
1	Systematic Name
23	Temperature Optimum [°C]
5	Temperature Range [°C]
50	Temperature Stability [°C]
126	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.47 - glucose 1-dehydrogenase [NAD(P)+]

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beta-D-glucose + NAD(P)(+)

D-glucono-1,5-lactone + NAD(P)H

Saccharolobus solfataricus

Q97U21

the enzyme might represent the major player in glucose catabolism via the branched Entner-Doudoroff pathway

718811

beta-D-glucose + NAD(P)+

D-glucono-1,5-lactone + NAD(P)H + H+

6 entries

beta-D-glucose + NADP+

D-glucono-1,5-lactone + NADPH + H+

Saccharolobus solfataricus

Q97U21

GDH-2 is absolutely specific for D-glucose. D-galactose, D-allose, D-mannose, D-xylose, L-arabinose, D-ribose, D-xylose, D-arabinose, L-xylose, D-glucosamine, 2-deoxy-D-glucose, D-fucose, D-lactose, D-maltose, D-fructose and ethanol were not used as substrates. kcat/Km of NADP+ is about 8fold higher compared to kcat/Km of NAD+

718811

D-glucose + NAD(P)+

D-glucono-1,5-lactone + NAD(P)H + H+

2 entries

D-glucose + NAD+

D-glucono-1,5-lactone + NADH + H+

8 entries

D-glucose + NADP+

D-glucono-1,5-lactone + NADPH + H+

8 entries