1.1.1.64: testosterone 17beta-dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about testosterone 17beta-dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

17-ketoreductase, 17beta-HSD, 17beta-HSD 3, 17beta-HSD type 3, 17beta-HSD type 5, 17beta-HSD-3, 17beta-HSD1, 17beta-HSD3, 17beta-HSD4, 17beta-HSD5, 17beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase 3, 17beta-hydroxysteroid dehydrogenase type 3, 17beta-hydroxysteroid dehydrogenase type 5, 17beta-hydroxysteroid dehydrogenases type 3, 17betaHSD3, 3beta-hydroxysteroid dehydrogenase type 3, AKR1C3, HSD17B3, More, NADP-dependent testosterone-17beta-oxidoreductase, type 3 17beta-HSD, type 3 17beta-hydroxysteroid dehydrogenase, type 5 17beta-hydroxysteroid dehydrogenase, type 5 beta-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)

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Results	in table
1	Activating Compound
24	AA Sequence
5	Application
1	CAS Registry Number
12	Cloned(Commentary)
57	Cofactor
6	Crystallization (Commentary)
31	Disease/ Diagnostics
5	Expression
17	General Information
1	General Stability
114	IC50 Value
231	Inhibitors
1	kcat/KM [mM/s]
12	Ki Value [mM]
31	KM Value [mM]
23	Localization
9	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
65	Organism
7	Pathway
52	PDB ID
12	pH Optimum
2	pH Range
16	Protein Variants
7	Purification (Commentary)
3	Reaction
3	Reaction Type
65	Reference
78	Source Tissue
7	Specific Activity [micromol/min/mg]
2	Storage Stability
112	Substrates and Products (Substrate)
1	Subunits
65	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

Synonyms

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Synonyms on EC 1.1.1.64 - testosterone 17beta-dehydrogenase (NADP+)

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

17-ketoreductase

-

-

-

-

17beta-HSD

Rattus norvegicus

O54939

-

699111

17beta-HSD 3

2 entries

17beta-HSD type 3

Homo sapiens

-

-

659587, 761760

17beta-HSD type 5

Homo sapiens

-

-

675981

17beta-HSD-3

Homo sapiens

-

-

658172

17beta-HSD1

Homo sapiens

-

-

675982

17beta-HSD3

5 entries

17beta-HSD4

Homo sapiens

-

-

675982

17beta-HSD5

Homo sapiens

P42330

-

739797

17beta-hydroxysteroid dehydrogenase

2 entries

17beta-hydroxysteroid dehydrogenase 3

2 entries

17beta-hydroxysteroid dehydrogenase type 3

6 entries

17beta-hydroxysteroid dehydrogenase type 5

Homo sapiens

-

-

675981, 712571

17beta-hydroxysteroid dehydrogenases type 3

Homo sapiens

-

-

657673

17betaHSD3

Homo sapiens

-

-

657673

3beta-hydroxysteroid dehydrogenase type 3

Homo sapiens

P37058

-

724536

AKR1C3

2 entries

HSD17B3

3 entries

NADP-dependent testosterone-17beta-oxidoreductase

-

-

-

-

type 3 17beta-HSD

3 entries

type 3 17beta-hydroxysteroid dehydrogenase

Homo sapiens

-

-

669784

type 5 17beta-hydroxysteroid dehydrogenase

Homo sapiens

P42330

-

739797

type 5 beta-hydroxysteroid dehydrogenase

Homo sapiens

P42330

-

724517

additional information

Homo sapiens

-

the enzyme belongs to the aldo-keto reductase family

675981

17beta-HSD 3

Danio rerio

-

-

669905

17beta-HSD 3

Homo sapiens

-

-

669905

17beta-HSD3

Homo sapiens

-

-

699845, 700187, 740162

17beta-HSD3

Homo sapiens

P37058

-

724550, 724555, 740916, 761168, 762479

17beta-HSD3

Rattus norvegicus

-

-

667983, 699845, 724555, 740143

17beta-HSD3

Rattus norvegicus

O54939

-

740916

17beta-HSD3

Rattus norvegicus Sprague-Dawley

O54939

-

-

17beta-hydroxysteroid dehydrogenase

Homo sapiens

-

-

675982

17beta-hydroxysteroid dehydrogenase

Rattus norvegicus

O54939

-

699111

17beta-hydroxysteroid dehydrogenase 3

Homo sapiens

-

-

699845

17beta-hydroxysteroid dehydrogenase 3

Rattus norvegicus

-

-

699845

17beta-hydroxysteroid dehydrogenase type 3

Danio rerio

-

-

669905

17beta-hydroxysteroid dehydrogenase type 3

Homo sapiens

-

-

658172, 669905, 700187, 740162

17beta-hydroxysteroid dehydrogenase type 3

Homo sapiens

P37058

-

740916, 761168, 762479

17beta-hydroxysteroid dehydrogenase type 3

Rattus norvegicus

-

-

667983, 740143

17beta-hydroxysteroid dehydrogenase type 3

Rattus norvegicus

O54939

-

740916

17beta-hydroxysteroid dehydrogenase type 3

Rattus norvegicus Sprague-Dawley

O54939

-

-

AKR1C3

Homo sapiens

-

-

675981, 712571

AKR1C3

Homo sapiens

P42330

-

723866, 724517, 724533, 724915, 739797, 740912

HSD17B3

Homo sapiens

-

-

761760

HSD17B3

Homo sapiens

P37058

-

740916

HSD17B3

Rattus norvegicus

O54939

-

740916

type 3 17beta-HSD

Canis lupus familiaris

-

-

658489

type 3 17beta-HSD

Homo sapiens

-

-

658489

type 3 17beta-HSD

Rattus norvegicus

-

-

658489