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1.1.1.69: gluconate 5-dehydrogenase

This is an abbreviated version!
For detailed information about gluconate 5-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.69

Reaction

D-gluconate
+
NAD(P)+
=
5-Dehydro-D-gluconate
+
NAD(P)H
+
H+

Synonyms

5-keto D-gluconate reductase, 5-keto-D-gluconate 5-reductase, 5-keto-D-gluconate reductase, 5-ketogluconate 5-reductase, 5-ketogluconate reductase, 5KGA reductase, 5KGR, dehydrogenase, gluconate 5-, GA5DH, gluconate 5-dehydrogenase, gluconate-5-dehydrogenase, gluconate:NADP 5-oxidoreductase, GluF, GNO, GOX2187 gene product, NADPH-dependent 5-keto-D-gluconate reductase, pyrroloquinoline quinone-dependent gluconate-5-dehydrogenase, QGA-5-DH, reductase, 5-ketogluconate 5-

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.69 gluconate 5-dehydrogenase

Reference

Reference on EC 1.1.1.69 - gluconate 5-dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Pitt, D.; Mosley, M.J.
Enzymes of gluconate metabolism and glycolysis in Penicillium notatum
Antonie van Leeuwenhoek
51
353-364
1985
Penicillium chrysogenum
Manually annotated by BRENDA team
Chiyonobu, T.; Shinagawa, E.; Adachi, O.; Ameyama, M.
Distribution of 2-ketogluconate reductase and 5-ketogluconate reductase in acetic acid bacteria
Agric. Biol. Chem.
39
2425-2427
1975
Acetobacter aceti, Acetobacter acetigenus, Acetobacter orleanensis, Acetobacter ascendens, Frateuria aurantia, Gluconobacter oxydans, Acetobacter pasteurianus, Komagataeibacter xylinus, Gluconobacter albidus, Gluconobacter cerinus, Gluconobacter gluconicus, Gluconacetobacter liquefaciens, Gluconobacter roseus, Gluconobacter sphaericus
-
Manually annotated by BRENDA team
Adachi, O.; Shinagawa, E.; Matsushita, K.; Ameyama, M.
Crystallization and properties of 5-keto-D-gluconate reductase from Gluconobacter suboxydans
Agric. Biol. Chem.
43
75-83
1979
Gluconobacter oxydans
-
Manually annotated by BRENDA team
Ameyama, M.; Adachi, O.
5-keto-D-Gluconate reductase from Gluconobacter suboxydans
Methods Enzymol.
89
198-202
1982
Gluconobacter oxydans
-
Manually annotated by BRENDA team
De Ley, J.
5-Ketogluconic acid reductase
Methods Enzymol.
9
200-203
1966
Gluconobacter oxydans, Escherichia coli, Klebsiella sp.
-
Manually annotated by BRENDA team
Ameyama, M.; Chiyonobu, T.; Adachi, O.
Purification and properties of 5-ketogluconate reductase from Gluconobacter liquefaciens
Agric. Biol. Chem.
38
1377-1382
1974
Gluconacetobacter liquefaciens
-
Manually annotated by BRENDA team
Klasen, R.; Bringer-Meyer, S.; Sahm, H.
Investigation of 5-ketogluconate formation by Gluconobacter oxydans
DECHEMA Biotechnol. Conf.
5
109-112
1992
Gluconobacter oxydans
-
Manually annotated by BRENDA team
Herrmann, U.; Merfort, M.; Jeude, M.; Bringer-Meyer, S.; Sahm, H.
Biotransformation of glucose to 5-keto-D-gluconic acid by recombinant Gluconobacter oxydans DSM 2343
Appl. Microbiol. Biotechnol.
64
86-90
2004
Gluconobacter oxydans
Manually annotated by BRENDA team
Salusjarvi, T.; Povelainen, M.; Hvorslev, N.; Eneyskaya, E.V.; Kulminskaya, A.A.; Shabalin, K.A.; Neustroev, K.N.; Kalkkinen, N.; Miasnikov, A.N.
Cloning of a gluconate/polyol dehydrogenase gene from Gluconobacter suboxydans IFO 12528, characterisation of the enzyme and its use for the production of 5-ketogluconate in a recombinant Escherichia coli strain
Appl. Microbiol. Biotechnol.
65
306-314
2004
Gluconobacter oxydans (Q70JN9), Gluconobacter oxydans (Q70JP0), Gluconobacter oxydans, Gluconobacter oxydans IFO 12528 (Q70JN9), Gluconobacter oxydans IFO 12528 (Q70JP0)
Manually annotated by BRENDA team
Elfari, M.; Ha, S.W.; Bremus, C.; Merfort, M.; Khodaverdi, V.; Herrmann, U.; Sahm, H.; Gorisch, H.
A Gluconobacter oxydans mutant converting glucose almost quantitatively to 5-keto-D-gluconic acid
Appl. Microbiol. Biotechnol.
66
668-674
2005
Gluconobacter oxydans
Manually annotated by BRENDA team
Merford, M.; Herrmann, U.; Bringer-Meyer, S.; Sahm, H.
High-yield 5-keto-D-gluconic acid formation is mediated by soluble and membrane-bound gluconate-5-dehydrogenases of Gluconobacter oxydans
Appl. Microbiol. Biotechnol.
73
443-4051
2006
Gluconobacter oxydans
Manually annotated by BRENDA team
Merford, M.; Herrmann, U.; Ha, S.W.; Elfari, M.; Ha, S.W.; Bringer-Meyer, S.; Goerisch, H.; Sahm, H.
Modification of the membrane-bound glucose oxidation system in Gluconobacter oxydans significantly increases gluconate and 5-keto-D-gluconic acid accumulation
J. Biotechnol.
1
556-563
2006
Gluconobacter oxydans, Gluconobacter oxydans DSM 2343 (ATCC 621H)
Manually annotated by BRENDA team
Saichana, I.; Ano, Y.; Adachi, O.; Matsushita, K.; Toyama, H.
Preparation of enzymes required for enzymatic quantification of 5-keto-D-gluconate and 2-keto-D-gluconate
Biosci. Biotechnol. Biochem.
71
2478-2486
2007
Gluconobacter oxydans
Manually annotated by BRENDA team
Zhang, Q.; Peng, H.; Gao, F.; Liu, Y.; Cheng, H.; Thompson, J.; Gao, G.F.
Structural insight into the catalytic mechanism of gluconate 5-dehydrogenase from Streptococcus suis: Crystal structures of the substrate-free and quaternary complex enzymes
Protein Sci.
18
294-303
2009
Streptococcus suis (A4VVQ2), Streptococcus suis
Manually annotated by BRENDA team
Chen, M.; Li, Y.; Li, S.; Tang, L.; Zheng, J.; An, Q.
Genomic identification of nitrogen-fixing Klebsiella variicola, K. pneumoniae and K. quasipneumoniae
J. Basic Microbiol.
56
78-84
2016
Klebsiella pneumoniae subsp. pneumoniae, Klebsiella pneumoniae subsp. rhinoscleromatis, Klebsiella quasipneumoniae subsp. similipneumoniae, Klebsiella variicola, Klebsiella quasipneumoniae subsp. quasipneumoniae, Klebsiella pneumoniae subsp. pneumoniae DSM 30104T, Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884T, Klebsiella quasipneumoniae subsp. quasipneumoniae 01A030T, Klebsiella quasipneumoniae subsp. similipneumoniae 07A044T, Klebsiella variicola DSM 15968T
Manually annotated by BRENDA team
Shi, Z.; Xuan, C.; Han, H.; Cheng, X.; Wang, J.; Feng, Y.; Srinivas, S.; Lu, G.; Gao, G.F.
Gluconate 5-dehydrogenase (Ga5DH) participates in Streptococcus suis cell division
Protein Cell
5
761-769
2014
Streptococcus suis, Streptococcus suis 05ZYH33
Manually annotated by BRENDA team
Kuivanen, J.; Richard, P.
NADPH-dependent 5-keto-D-gluconate reductase is a part of the fungal pathway for D-glucuronate catabolism
FEBS Lett.
592
71-77
2018
Aspergillus niger (G3XRE5), Aspergillus niger, Aspergillus niger ATCC 1015 (G3XRE5)
Manually annotated by BRENDA team
Tian, D.; Fu, X.; Cao, W.; Yuan, H.
Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum
Acta Crystallogr. Sect. F
76
228-234
2020
Lentibacter algarum (A0A1H3NGY9), Lentibacter algarum
Manually annotated by BRENDA team