1.1.1.B38: hydroxymethylglutaryl-CoA reductase [NAD(P)H]
This is an abbreviated version!
For detailed information about hydroxymethylglutaryl-CoA reductase [NAD(P)H], go to the full flat file.
Reaction
+ + 2 NAD(P)+ = + 2 NAD(P)H + 2 H+
Synonyms
3-hydroxy-3-methylglutaryl coenzyme A reductase, AF1736, class II HMG-CoA reductase, HGMR, HMG-CoA reductase
ECTree
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pH Optimum
pH Optimum on EC 1.1.1.B38 - hydroxymethylglutaryl-CoA reductase [NAD(P)H]
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6
reductive deacylation of 3-hydroxy-3-methylglutaryl-CoA to mevalonate with NADPH
6.8
oxidative acylation of mevalonate to 3-hydroxy-3-methylglutaryl-CoA with NADP+
9
reductive deacylation of 3-hydroxy-3-methylglutaryl-CoA to mevalonate with NADH
9.5 - 10
oxidative acylation of mevalonate to 3-hydroxy-3-methylglutaryl-CoA with NAD+