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1.1.1.B47: succinate semialdehyde reductase (NADPH)

This is an abbreviated version!
For detailed information about succinate semialdehyde reductase (NADPH), go to the full flat file.

Word Map on EC 1.1.1.B47

Reaction

4-hydroxybutanoate
+
NADP+
=
succinate semialdehyde
+
NADPH
+
H+

Synonyms

At3g25530, AtGLYR1, Msed_1424, SSA, succinate semialdehyde reductase, succinic semialdehyde reductase, succinic semialdehyde reductase (NADPH)

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B47 succinate semialdehyde reductase (NADPH)

Engineering

Engineering on EC 1.1.1.B47 - succinate semialdehyde reductase (NADPH)

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D239A
site-directed mutagenesis
F231A
site-directed mutagenesis
K170A
site-directed mutagenesis, catalytically inactive mutant
K170E
site-directed mutagenesis, the mutant shows highly reduced kcat for glyoxylate compared to the wild-type
K170H
site-directed mutagenesis, the mutant shows highly reduced kcat for glyoxylate compared to the wild-type
K170R
site-directed mutagenesis, the mutant shows highly reduced kcat for glyoxylate compared to the wild-type
N174A
site-directed mutagenesis
S121A
site-directed mutagenesis
T95A
site-directed mutagenesis