1.1.1.B47: succinate semialdehyde reductase (NADPH)
This is an abbreviated version!
For detailed information about succinate semialdehyde reductase (NADPH), go to the full flat file.
Word Map on EC 1.1.1.B47
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1.1.1.B47
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gamma-hydroxybutyrate
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ssars
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aldo-keto
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sulfurreducens
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gaba-t
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geobacter
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4-hydroxybutyrate
- 1.1.1.B47
- gamma-hydroxybutyrate
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ssars
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aldo-keto
- sulfurreducens
- gaba-t
- geobacter
- 4-hydroxybutyrate
Reaction
Synonyms
At3g25530, AtGLYR1, Msed_1424, SSA, succinate semialdehyde reductase, succinic semialdehyde reductase, succinic semialdehyde reductase (NADPH)
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Natural Substrates Products on EC 1.1.1.B47 - succinate semialdehyde reductase (NADPH)
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REACTION DIAGRAM
succinic semialdehyde + NADPH + H+
4-hydroxybutyrate + NADP+
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additional information
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the recombinant AtGLYR1 prefers NADPH over NADH and converts glyoxylate to glycolate, the enzyme has negligible hydroxypyruvate-dependent activity. Isozyme AtGLYR1 also converts succinic semialdehyde to gamma-hydroxybutyrate, albeit with much lower catalytic efficiency than for glyoxylate
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4-hydroxybutanoate + NADP+
the enzyme participates in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea
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succinate semialdehyde + NADPH + H+
4-hydroxybutanoate + NADP+
the enzyme participates in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea
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