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1.1.1.B65: (R)-mandelate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about (R)-mandelate dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

Synonyms

RMDH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.B65 (R)-mandelate dehydrogenase [NAD(P)+]

Inhibitors

Inhibitors on EC 1.1.1.B65 - (R)-mandelate dehydrogenase [NAD(P)+]

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ca2+
-
inhibits 4% aT 1 mM and 33% at 10 mM
EDTA
-
inhibits the enzyme activity about 68% and 89% in the concentration of 10 mM and 50 mM,respectively
Hg2+
-
strong inhibition at 1 mM
Li+
-
inhibits 17% at 10 mM
Mg2+
-
inhibits 19% at 1 mM and 31% at 10 mM
Mn2+
-
21% activation at 1 mM, and 61% inhibition at 10 mM
Ni2+
-
inhibits 39% at 1 mM and 63% at 10 mM
SDS
-
strongly inhibits the enzyme activity at 0.25-0.75%
Triton X-100
-
0.25% of TritonX-100 has slight improvement on enzyme activity, whereas 0.75% of TritonX-100 slightly inhibits the enzyme activity
Zn2+
-
strong inhibition at 10 mM