1.1.5.B3: quinone dependent L-lactate dehydrogenase
This is an abbreviated version!
For detailed information about quinone dependent L-lactate dehydrogenase, go to the full flat file.
Reaction
Synonyms
LldD, PQQ-dependent lactate dehydrogenase, PQQ-LDH, quinone-dependent L-lactate dehydrogenase
ECTree
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Engineering
Engineering on EC 1.1.5.B3 - quinone dependent L-lactate dehydrogenase
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additional information
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disruption of the ldhD-NCgl2816 operon results in loss of the ability to utilize L-lactate as sole carbon source, the ability can be restored by expression of gene ldhD, overview
additional information
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overexpression of the regulator gene lldR results in strongly reduced NCgl2816-lldD mRNA levels and strongly reduced LldD activity, and as a consequence, in a severe growth defect was observed in cells grown on L-lactate as the sole carbon and energy source, but not in cells grown on glucose, ribose, or acetate. Deletion of lldR has no effect on growth on these carbon sources but results in high NCgl2816-lldD mRNA levels and high LldD activity in the presence and absence of L-lactate, overview
additional information
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bioanode fabrication using the partially purified enzyme immobilized on a membrane, usage of carbon fiber paper, overview
additional information
Gluconobacter sp. DSM 3504 / ATCC 15163
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bioanode fabrication using the partially purified enzyme immobilized on a membrane, usage of carbon fiber paper, overview
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