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1.1.99.6: D-lactate dehydrogenase (acceptor)

This is an abbreviated version!
For detailed information about D-lactate dehydrogenase (acceptor), go to the full flat file.

Word Map on EC 1.1.99.6

Reaction

(R)-lactate
+
acceptor
=
pyruvate
+
reduced acceptor

Synonyms

AF0394, APE_0487, CSUB_C1080, D-2-hydroxy acid dehydrogenase, dehydrogenase, D-2-hydroxy acid, Dld enzyme, dye-DLDH, dye-linked D-lactate dehydrogenase, ST0649, TTX_0794

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.6 D-lactate dehydrogenase (acceptor)

Application

Application on EC 1.1.99.6 - D-lactate dehydrogenase (acceptor)

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
analysis
diagnostics
D-lactate content is of great interest for clinical diagnosis. A D-lactate sensing system using a thermostable dye-linked D-lactate dehydrogenase (Dye-DLDH) is developed. The electrode for detection of D-lactate is prepared by immobilizing the thermostable Dye-DLDH and multi-walled carbon nanotube (MWCNT) within Nafion membrane. The electrocatalytic response of the electrode is clearly observed upon exposure to D-lactate. The electrode response to D-lactate is linear within the concentration range of 0.03-2.5 mM, and it shows little reduction in responsiveness after 50 days
synthesis
-
production of pyruvate in an enzyme-membrane reactor