Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.11.1.10: chloride peroxidase

This is an abbreviated version!
For detailed information about chloride peroxidase, go to the full flat file.

Word Map on EC 1.11.1.10

Reaction

RH
+
chloride
+
H2O2
=
RCl
+ 2 H2O

Synonyms

CCPO, Chloride peroxidase, chloroperoxidase, chloroproxidase, CPO, CPO-I, CPO2, haeme-thiolate peroxidase, heme-containing CPO, heme-thiolate chloroperoxidase, More, peroxidase, chloride, Vanadium chloride peroxidase, vCPO

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.10 chloride peroxidase

Crystallization

Crystallization on EC 1.11.1.10 - chloride peroxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
chloroperoxidase A and B
-
hanging drop method, crystal structures of chloroperoxidase with its bound substrates and complexed with formate, acetate, and nitrate
-
molecular docking. Orange G binds within the wide channel of CPO
-
sitting drop vapor diffusion method, crystals are modified by several cross-linkers, but only glutaraldehyde is able to produce catalytically active and insoluble crystals. Although the cross-linked crystals are catalytically active, they show lower specific activity than the soluble enzyme
-
structure model comparison of isoforms CPO and CPO2, high conservation of the active site and the substrate channel. Amino acids Cys30, Met62, Met154 and Trp226 of CPO, which are oxidized upon treatment of the enzyme with a CPO-inactivating H 2 O 2 concentration, are also contained in CPO2