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1.11.1.21: catalase-peroxidase

This is an abbreviated version!
For detailed information about catalase-peroxidase, go to the full flat file.

Word Map on EC 1.11.1.21

Reaction

2 H2O2 =

O2
+ 2 H2O

Synonyms

AfKatG, BW16_04845, CAT, CAT-2, catalase -peroxidase KatG, catalase peroxidase, catalase-peroxidase, catalase/peroxidase, CP 2, CP01, CP02, CPX, CthediskatG, EC 1.11.1.7, FeSOD A, FvCP01, FvCP02, FVEG_10866, FVEG_12888, HCP, hemoprotein b-590, HPI, hydroperoxidase I, KatG, KatG1, KatG2, KatP, katX2, KpCP, PCP, Rv1908c

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.21 catalase-peroxidase

Reference

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Reference on EC 1.11.1.21 - catalase-peroxidase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Johnsson, K.; Froland, W.A.; Schultz, P.G.
Overexpression, purification, and characterization of the catalase-peroxidase KatG from Mycobacterium tuberculosis
J. Biol. Chem.
272
2834-2840
1997
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Fraaije, M.W.; Roubroeks, H.P.; Hagen, W.R.; Van Berkel, W.J.
Purification and characterization of an intracellular catalase-peroxidase from Penicillium simplicissimum
Eur. J. Biochem.
235
192-198
1996
Penicillium simplicissimum, Penicillium simplicissimum CBS 170.90
Manually annotated by BRENDA team
Brown-Petersen, N.J.; Salin, M.L.
Purification of a catalase-peroxidase from Halobacterium halobium: Characterization of some unique properties of the halophilic enzyme
J. Bacteriol.
175
4197-4202
1993
Halobacterium salinarum
Manually annotated by BRENDA team
Hochman, A.; Shemesh, A.
Purification and characterization of a catalase-peroxidase from the photosynthetic bacterium Rhodopseudomonas capsulata
J. Biol. Chem.
262
6871-6876
1987
Rhodobacter capsulatus
Manually annotated by BRENDA team
Carpena, X.; Switala, J.; Loprasert, S.; Mongkolsuk, S.; Fita, I.; Loewen, P.C.
Crystallization and preliminary X-ray analysis of the catalase-peroxidase KatG from Burkholderia pseudomallei
Acta Crystallogr. Sect. D
58
2184-2186
2002
Burkholderia pseudomallei (Q939D2), Burkholderia pseudomallei
Manually annotated by BRENDA team
Wei, C.J.; Lei, B.; Musser, J.M.; Tu, S.C.
Isoniazid activation defects in recombinant Mycobacterium tuberculosis catalase-peroxidase (KatG) mutants evident in InhA inhibitor production
Antimicrob. Agents Chemother.
47
670-675
2003
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Varnado, C.L.; Hertwig, K.M.; Thomas, R.; Roberts, J.K.; Goodwin, D.C.
Properties of a novel periplasmic catalase-peroxidase from Escherichia coli O157:H7
Arch. Biochem. Biophys.
421
166-174
2004
Escherichia coli
Manually annotated by BRENDA team
Jakopitsch, C.; Auer, M.; Regelsberger, G.; Jantschko, W.; Furtmuller, P.G.; Ruker, F.; Obinger, C.
Distal site aspartate is essential in the catalase activity of catalase-peroxidases
Biochemistry
42
5292-5300
2003
Synechocystis sp.
Manually annotated by BRENDA team
Santoni, E.; Jakopitsch, C.; Obinger, C.; Smulevich, G.
Comparison between catalase-peroxidase and cytochrome c peroxidase. The role of the hydrogen-bond network for protein stability and catalysis
Biochemistry
43
5792-5802
2004
Synechocystis sp. PCC 6803
Manually annotated by BRENDA team
Kapetanaki, S.M.; Chouchane, S.; Yu, S.; Zhao, X.; Magliozzo, R.S.; Schelvis, J.P.
Mycobacterium tuberculosis KatG(S315T) catalase-peroxidase retains all active site properties for proper catalytic function
Biochemistry
44
243-252
2005
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Ro, Y.T.; Lee, H.I.; Kim, E.J.; Koo, J.H.; Kim, E.; Kim, Y.M.
Purification, characterization, and physiological response of a catalase-peroxidase in Mycobacterium sp. strain JC1 DSM 3803 grown on methanol
FEMS Microbiol. Lett.
226
397-403
2003
Mycobacterium sp., Mycobacterium sp. JC1 DSM 3803
Manually annotated by BRENDA team
Donald, L.J.; Krokhin, O.V.; Duckworth, H.W.; Wiseman, B.; Deemagarn, T.; Singh, R.; Switala, J.; Carpena, X.; Fita, I.; Loewen, P.C.
Characterization of the catalase-peroxidase KatG from Burkholderia pseudomallei by mass spectrometry
J. Biol. Chem.
278
35687-35692
2003
Burkholderia pseudomallei
Manually annotated by BRENDA team
Ghiladi, R.A.; Knudsen, G.M.; Medzihradszky, K.F.; Ortiz de Montellano, P.R.
The Met-Tyr-Trp cross-link in Mycobacterium tuberculosis catalase-peroxidase (KatG): autocatalytic formation and effect on enzyme catalysis and spectroscopic properties
J. Biol. Chem.
280
22651-22663
2005
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Jakopitsch, C.; Wanasinghe, A.; Jantschko, W.; Furtmueller, P.G.; Obinger, C.
Kinetics of interconversion of ferrous enzymes, compound II and compound III, of wild-type synechocystis catalase-peroxidase and Y249F: proposal for the catalatic mechanism
J. Biol. Chem.
280
9037-9042
2005
Synechocystis sp.
Manually annotated by BRENDA team
Deemagarn, T.; Wiseman, B.; Carpena, X.; Ivancich, A.; Fita, I.; Loewen, P.C.
Two alternative substrate paths for compound I formation and reduction in catalase-peroxidase KatG from Burkholderia pseudomallei
Proteins
66
219-228
2007
Burkholderia pseudomallei
Manually annotated by BRENDA team
Moore, R.L.; Powell, L.J.; Goodwin, D.C.
The kinetic properties producing the perfunctory pH profiles of catalase-peroxidases
Biochim. Biophys. Acta
1784
900-907
2008
Escherichia coli
Manually annotated by BRENDA team
Charalabous, P.; Risk, J.M.; Jenkins, R.; Birss, A.J.; Hart, C.A.; Smalley, J.W.
Characterization of a bifunctional catalase-peroxidase of Burkholderia cenocepacia
FEMS Immunol. Med. Microbiol.
50
37-44
2007
Burkholderia cenocepacia
Manually annotated by BRENDA team
Moore, R.L.; Cook, C.O.; Williams, R.; Goodwin, D.C.
Substitution of strictly conserved Y111 in catalase-peroxidases: Impact of remote interdomain contacts on active site structure and catalytic performance
J. Inorg. Biochem.
102
1819-1824
2008
Escherichia coli
Manually annotated by BRENDA team
Zamocky, M.; Furtmueller, P.G.; Bellei, M.; Battistuzzi, G.; Stadlmann, J.; Vlasits, J.; Obinger, C.
Intracellular catalase/peroxidase from the phytopathogenic rice blast fungus Magnaporthe grisea: expression analysis and biochemical characterization of the recombinant protein
Biochem. J.
418
443-451
2009
Pyricularia grisea (A4QUT2), Pyricularia grisea (A4R5S9), Pyricularia grisea, Pyricularia grisea ATCC MYA-4617 (A4QUT2), Pyricularia grisea ATCC MYA-4617 (A4R5S9)
Manually annotated by BRENDA team
Zhao, X.; Yu, S.; Ranguelova, K.; Suarez, J.; Metlitsky, L.; Schelvis, J.P.; Magliozzo, R.S.
Role of the oxyferrous heme intermediate and distal side adduct radical in the catalase activity of Mycobacterium tuberculosis KatG revealed by the W107F mutant
J. Biol. Chem.
284
7030-7037
2009
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5)
Manually annotated by BRENDA team
Calandrelli, V.; Gambacorta, A.; Romano, I.; Carratore, V.; Lama, L.
A novel thermo-alkali stable catalase-peroxidase from Oceanobacillus oncorhynchi subsp. incaldaniensis: Purification and characterization
World J. Microbiol. Biotechnol.
24
2269-2275
2008
Oceanobacillus oncorhynchi subsp. incaldanensis, Oceanobacillus oncorhynchi subsp. incaldanensis 20AG
-
Manually annotated by BRENDA team
Singh, R.; Wiseman, B.; Deemagarn, T.; Jha, V.; Switala, J.; Loewen, P.
Comparative study of catalase-peroxidases (KatGs)
Arch. Biochem. Biophys.
471
207-214
2008
Archaeoglobus fulgidus, Burkholderia pseudomallei, Escherichia coli, Geobacillus stearothermophilus, Mycobacterium tuberculosis, Rhodobacter capsulatus, Synechocystis sp.
Manually annotated by BRENDA team
Vlasits, J.; Jakopitsch, C.; Bernroitner, M.; Zamocky, M.; Furtmueller, P.G.; Obinger, C.
Mechanisms of catalase activity of heme peroxidases
Arch. Biochem. Biophys.
500
74-81
2010
Haloarcula marismortui (O59651), Mycobacterium tuberculosis (P9WIE5), Synechococcus elongatus (Q31MN3), Burkholderia pseudomallei (Q939D2), Mycobacterium tuberculosis H37Rv (P9WIE5), Synechococcus elongatus PCC 7942 (Q31MN3)
Manually annotated by BRENDA team
Obinger, C.; Regelsberger, G.; Strasser, G.; Burner, U.; Peschek, G.A.
Purification and characterization of a homodimeric catalase-peroxidase from the cyanobacterium Anacystis nidulans
Biochem. Biophys. Res. Commun.
235
545-552
1997
Synechococcus elongatus PCC 7942 = FACHB-805
Manually annotated by BRENDA team
Li, Y.; Goodwin, D.C.
Vital roles of an interhelical insertion in catalase-peroxidase bifunctionality
Biochem. Biophys. Res. Commun.
318
970-976
2004
Escherichia coli
Manually annotated by BRENDA team
Nagy, J.; Jesmin, J.; Servos, S.; Cass, A.; Brown, K.
Site-directed mutants of the catalase-peroxidase from Mycobacterium tuberculosis
Biochem. Soc. Trans.
26
S281
1998
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Hillar, A.; Peters, B.; Pauls, R.; Loboda, A.; Zhang, H.; Mauk, A.G.; Loewen, P.C.
Modulation of the activities of catalase-peroxidase HPI of Escherichia coli by site-directed mutagenesis
Biochemistry
39
5868-5875
2000
Escherichia coli, Escherichia coli UM262
Manually annotated by BRENDA team
Chouchane, S.; Lippai, I.; Magliozzo, R.S.
Catalase-peroxidase (Mycobacterium tuberculosis KatG) catalysis and isoniazid activation
Biochemistry
39
9975-9983
2000
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Hochman, A.; Goldberg, I.
Purification and characterization of a catalase-peroxidase and a typical catalase from the bacterium Klebsiella pneumoniae
Biochim. Biophys. Acta
1077
299-307
1991
Klebsiella pneumoniae, Klebsiella pneumoniae KP1
Manually annotated by BRENDA team
Cendrin, F.; Jouve, H.M.; Gaillard, J.; Thibault, P.; Zaccai, G.
Purification and properties of a halophilic catalase-peroxidase from Haloarcula marismortui
Biochim. Biophys. Acta
1209
1-9
1994
Haloarcula marismortui
Manually annotated by BRENDA team
Vlasits, J.; Furtmueller, P.G.; Jakopitsch, C.; Zamocky, M.; Obinger, C.
Probing hydrogen peroxide oxidation kinetics of wild-type Synechocystis catalase-peroxidase (KatG) and selected variants
Biochim. Biophys. Acta
1804
799-805
2010
Synechocystis sp.
Manually annotated by BRENDA team
Jakopitsch, C.; Rueker, F.; Regelsberger, G.; Dockal, M.; Peschek, G.A.; Obinger, C.
Catalase-peroxidase from the cyanobacterium Synechocystis PCC 6803: cloning, overexpression in Escherichia coli, and kinetic characterization
Biol. Chem.
380
1087-1096
1999
Synechocystis sp.
Manually annotated by BRENDA team
Eady, N.A.; Jesmin, N.A.; Servos, S.; Cass, A.E.; Nagy, J.M.; Brown, K.A.
Probing the function of Mycobacterium tuberculosis catalase-peroxidase by site-directed mutagenesis
Dalton Trans.
2005
3495-3500
2005
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Jakopitsch, C.; Auer, M.; Regelsberger, G.; Jantschko, W.; Furtmüller, P.; Rüker, F.; Obinger, C.
The catalytic role of the distal site asparagine-histidine couple in catalase-peroxidases
Eur. J. Biochem.
270
1006-1013
2003
Synechocystis sp.
Manually annotated by BRENDA team
Kengen, S.W.; Bikker, F.J.; Hagen, W.R.; de Vos, W.M.; van der Oost, J.
Characterization of a catalase-peroxidase from the hyperthermophilic archaeon Archaeoglobus fulgidus
Extremophiles
5
323-332
2001
Archaeoglobus fulgidus (O28050), Archaeoglobus fulgidus
Manually annotated by BRENDA team
Vlasits, J.; Jakopitsch, C.; Schwanninger, M.; Holubar, P.; Obinger, C.
Hydrogen peroxide oxidation by catalase-peroxidase follows a non-scrambling mechanism
FEBS Lett.
581
320-324
2007
Synechocystis sp., Mycobacterium tuberculosis
Manually annotated by BRENDA team
Italiani, V.C.; Braz, V.S.; Xiao, H.; Steinman, H.M.; Marques, M.V.
Catalase-peroxidase activity is decreased in a Caulobacter crescentus rho mutant
FEMS Microbiol. Lett.
303
48-54
2010
Caulobacter vibrioides
Manually annotated by BRENDA team
Appleby, C.; Poole, R.
Characterization of a soluble catalase-peroxidase hemoprotein b-590, previously identified as cytochrome a1 from Bradyrhizobium japonicum bacteroids
FEMS Microbiol. Lett.
78
325-331
1991
Bradyrhizobium japonicum, Bradyrhizobium japonicum CC705
Manually annotated by BRENDA team
Loewen, P.C.; Triggs, B.L.; George, C.S.; Hrabarchuk, B.E.
Genetic mapping of katG, a locus that affects synthesis of the bifunctional catalase-peroxidase hydroperoxidase I in Escherichia coli
J. Bacteriol.
162
661-667
1985
Escherichia coli
Manually annotated by BRENDA team
Steinman, H.M.; Fareed, F.; Weinstein, L.
Catalase-peroxidase of Caulobacter crescentus: function and role in stationary-phase survival
J. Bacteriol.
179
6831-6836
1997
Caulobacter vibrioides (O31066), Caulobacter vibrioides
Manually annotated by BRENDA team
Tichy, M.; Vermaas, W.
In vivo role of catalase-peroxidase in Synechocystis sp. strain PCC 6803
J. Bacteriol.
181
1875-1882
1999
Synechocystis sp. (P73911), Synechocystis sp.
Manually annotated by BRENDA team
Jittawuttipoka, T.; Buranajitpakorn, S.; Vattanaviboon, P.; Mongkolsuk, S.
The catalase-peroxidase KatG is required for virulence of Xanthomonas campestris pv. campestris in a host plant by providing protection against low levels of H2O2
J. Bacteriol.
191
7372-7377
2009
Xanthomonas campestris pv. campestris
Manually annotated by BRENDA team
Marcinkeviciene, J.A.; Magliozzo, R.S.; Blanchard, J.S.
Purification and characterization of the Mycobacterium smegmatis catalase-peroxidase involved in isoniazid activation
J. Biol. Chem.
270
22290-22295
1995
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
Manually annotated by BRENDA team
Nagy, J.M.; Cass, A.E.; Brown, K.A.
Purification and characterization of recombinant catalase-peroxidase, which confers isoniazid sensitivity in Mycobacterium tuberculosis
J. Biol. Chem.
272
31265-31271
1997
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Bertrand, T.; Eady, N.A.; Jones, J.N.; Jesmin, J.N.; Nagy, J.M.; Jamart-Gregoire, B.; Raven, E.L.; Brown, K.A.
Crystal structure of Mycobacterium tuberculosis catalase-peroxidase
J. Biol. Chem.
279
38991-38999
2004
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5)
Manually annotated by BRENDA team
Wiseman, B.; Colin, J.; Smith, A.T.; Ivancich, A.; Loewen, P.C.
Mechanistic insight into the initiation step of the reaction of Burkholderia pseudomallei catalase-peroxidase with peroxyacetic acid
J. Biol. Inorg. Chem.
14
801-811
2009
Burkholderia pseudomallei
Manually annotated by BRENDA team
Wengenack, N.L.; Uhl, J.R.; St Amand, A.L.; Tomlinson, A.J.; Benson, L.M.; Naylor, S.; Kline, B.C.; Cockerill, F.R.; Rusnak, F.
Recombinant Mycobacterium tuberculosis KatG(S315T) is a competent catalase-peroxidase with reduced activity toward isoniazid
J. Infect. Dis.
176
722-727
1997
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Smulevich, G.; Jakopitsch, C.; Droghetti, E.; Obinger, C.
Probing the structure and bifunctionality of catalase-peroxidase (KatG)
J. Inorg. Biochem.
100
568-585
2006
Escherichia coli, Mycobacterium tuberculosis (P9WIE5), Synechococcus sp. (Q31MN3), Burkholderia pseudomallei (Q939D2), Synechococcus sp. PCC 7942 (Q31MN3), Mycobacterium tuberculosis H37Rv (P9WIE5)
Manually annotated by BRENDA team
Kapetanaki, S.M.; Chouchane, S.; Yu, S.; Magliozzo, R.S.; Schelvis, J.P.
Resonance Raman spectroscopy of Compound II and its decay in Mycobacterium tuberculosis catalase-peroxidase KatG and its isoniazid resistant mutant S315T
J. Inorg. Biochem.
99
1401-1406
2005
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Carpena, X.; Loprasert, S.; Mongkolsuk, S.; Switala, J.; Loewen, P.C.; Fita, I.
Catalase-peroxidase KatG of Burkholderia pseudomallei at 1.7A resolution
J. Mol. Biol.
327
475-489
2003
Burkholderia pseudomallei (Q939D2), Burkholderia pseudomallei
Manually annotated by BRENDA team
Heym, B.; Alzari, P.M.; Honore, N.; Cole, S.T.
Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis
Mol. Microbiol.
15
235-245
1995
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Rouse, D.A.; DeVito, J.A.; Li, Z.; Byer, H.; Morris, S.L.
Site-directed mutagenesis of the katG gene of Mycobacterium tuberculosis: effects on catalase-peroxidase activities and isoniazid resistance
Mol. Microbiol.
22
583-592
1996
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Deemagarn, T.; Wiseman, B.; Carpena, X.; Ivancich, A.; Fita, I.; Loewen, P.C.
Two alternative substrate paths for compound I formation and reduction in catalase-peroxidase KatG from Burkholderia pseudomallei
Proteins Struct. Funct. Bioinform.
66
219-228
2007
Burkholderia pseudomallei (Q939D2), Burkholderia pseudomallei
Manually annotated by BRENDA team
Di Gennaro, P.; Bargna, A.; Bruno, F.; Sello, G.
Purification of recombinant catalase-peroxidase HPI from E. coli and its application in enzymatic polymerization reactions
Appl. Microbiol. Biotechnol.
98
1119-1126
2014
Escherichia coli (B1IVD5), Escherichia coli, Escherichia coli DSM 1576 (B1IVD5)
Manually annotated by BRENDA team
Ndontsa, E.N.; Moore, R.L.; Goodwin, D.C.
Stimulation of KatG catalase activity by peroxidatic electron donors
Arch. Biochem. Biophys.
525
215-222
2012
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Ivancich, A.; Donald, L.J.; Villanueva, J.; Wiseman, B.; Fita, I.; Loewen, P.C.
Spectroscopic and kinetic investigation of the reactions of peroxyacetic acid with Burkholderia pseudomallei catalase-peroxidase, KatG
Biochemistry
52
7271-7282
2013
Burkholderia pseudomallei
Manually annotated by BRENDA team
Wang, Y.; Goodwin, D.C.
Integral role of the I-helix in the function of the "inactive" C-terminal domain of catalase-peroxidase (KatG)
Biochim. Biophys. Acta
1834
362-371
2013
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Sangar, S.; Pal, M.; Moon, L.S.; Jolly, R.S.
A catalase-peroxidase for oxidation of beta-lactams to their (R)-sulfoxides
Biores. Technol.
115
102-110
2012
Bacillus pumilus
Manually annotated by BRENDA team
Zamocky, M.; Garcia-Fernandez, Q.; Gasselhuber, B.; Jakopitsch, C.; Furtmueller, P.G.; Loewen, P.C.; Fita, I.; Obinger, C.; Carpena, X.
High conformational stability of secreted eukaryotic catalase-peroxidases: answers from first crystal structure and unfolding studies
J. Biol. Chem.
287
32254-32262
2012
Pyricularia grisea (A4QUT2), Pyricularia grisea ATCC MYA-4617 (A4QUT2)
Manually annotated by BRENDA team
Zhao, X.; Khajo, A.; Jarrett, S.; Suarez, J.; Levitsky, Y.; Burger, R.M.; Jarzecki, A.A.; Magliozzo, R.S.
Specific function of the Met-Tyr-Trp adduct radical and residues Arg-418 and Asp-137 in the atypical catalase reaction of catalase-peroxidase KatG
J. Biol. Chem.
287
37057-37065
2012
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Kudalkar, S.N.; Campbell, R.A.; Li, Y.; Varnado, C.L.; Prescott, C.; Goodwin, D.C.
Enhancing the peroxidatic activity of KatG by deletion mutagenesis
J. Inorg. Biochem.
116
106-115
2012
Escherichia coli
Manually annotated by BRENDA team
Yamada, Y.; Saijo, S.; Sato, T.; Igarashi, N.; Usui, H.; Fujiwara, T.; Tanaka, N.
Crystallization and preliminary X-ray analysis of catalase-peroxidase from the halophilic archaeon Haloarcula marismortui
Acta Crystallogr. Sect. D
57
1157-1158
2001
Haloarcula marismortui (O59651), Haloarcula marismortui, Haloarcula marismortui DSM 3752 (O59651)
Manually annotated by BRENDA team
Cannac-Caffrey, V.; Hudry-Clergeon, G.; Petillot, Y.; Gagnon, J.; Zaccai, G.; Franzetti, B.
The protein sequence of an archaeal catalase-peroxidase
Biochimie
80
1003-1011
1998
Haloarcula marismortui (O59651), Haloarcula marismortui, Haloarcula marismortui DSM 3752 (O59651)
Manually annotated by BRENDA team
Yamada, Y.; Fujiwara, T.; Sato, T.; Igarashi, N.; Tanaka, N.
The 2.0 A crystal structure of catalase-peroxidase from Haloarcula marismortui
Nat. Struct. Biol.
9
691-695
2002
Haloarcula marismortui (O59651), Haloarcula marismortui, Haloarcula marismortui DSM 3752 (O59651)
Manually annotated by BRENDA team
Kamachi, S.; Wada, K.; Tamoi, M.; Shigeoka, S.; Tada, T.
The 2.2 A resolution structure of the catalase-peroxidase KatG from Synechococcus elongatus PCC7942
Acta Crystallogr. Sect. F
70
288-293
2014
Synechococcus elongatus (Q31MN3), Synechococcus elongatus PCC7942 (Q31MN3)
Manually annotated by BRENDA team
Chioti, V.; Zervoudakis, G.
Is root catalase a bifunctional catalase-peroxidase?
Antioxidants (Basel)
6
39
2017
Solanum lycopersicum, Solanum melongena
Manually annotated by BRENDA team
Chioti, V.; Zervoudakis, G.
Is root catalase a bifunctional catalase-peroxidase?
Antioxidants (Basel)
6
E39
2017
Cichorium endivia, Lactuca sativa
Manually annotated by BRENDA team
Njuma, O.; Ndontsa, E.; Goodwin, D.
Catalase in peroxidase clothing Interdependent cooperation of two cofactors in the catalytic versatility of KatG
Arch. Biochem. Biophys.
544
27-39
2014
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Kudalkar, S.N.; Njuma, O.J.; Li, Y.; Muldowney, M.; Fuanta, N.R.; Goodwin, D.C.
A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis control of active site water and ferric enzyme reactivity
Biochemistry
54
1648-1662
2015
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Gasselhuber, B.; Graf, M.M.; Jakopitsch, C.; Zamocky, M.; Nicolussi, A.; Furtmueller, P.G.; Oostenbrink, C.; Carpena, X.; Obinger, C.
Interaction with the redox cofactor MYW and functional role of a mobile arginine in eukaryotic catalase-peroxidase
Biochemistry
55
3528-3541
2016
Pyricularia grisea (A4QUT2), Pyricularia grisea, Pyricularia grisea 70-15 (A4QUT2)
Manually annotated by BRENDA team
Ganini, D.; Petrovich, R.M.; Edwards, L.L.; Mason, R.P.
Iron incorporation into MnSOD A (bacterial Mn-dependent superoxide dismutase) leads to the formation of a peroxidase/catalase implicated in oxidative damage to bacteria
Biochim. Biophys. Acta
1850
1795-1805
2015
Escherichia coli
Manually annotated by BRENDA team
Zamocky, M.; Gasselhuber, B.; Furtmueller, P.G.; Obinger, C.
Turning points in the evolution of peroxidase-catalase superfamily molecular phylogeny of hybrid heme peroxidases
Cell. Mol. Life Sci.
71
4681-4696
2014
Burkholderia pseudomallei
Manually annotated by BRENDA team
Latawa, R.; Singh, K.K.; Wanchu, A.; Sethi, S.; Sharma, K.; Sharma, A.; Laal, S.; Verma, I.
Specific amplification of gene encoding N-terminal region of catalase-peroxidase protein (KatG-N) for diagnosis of disseminated MAC disease in HIV patients
Diagn. Microbiol. Infect. Dis.
80
122-129
2014
Mycobacterium avium, Mycobacterium avium 104
Manually annotated by BRENDA team
Kamachi, S.; Hirabayashi, K.; Tamoi, M.; Shigeoka, S.; Tada, T.; Wada, K.
The crystal structure of isoniazid-bound KatG catalase-peroxidase from Synechococcuselongatus PCC7942
FEBS J.
282
54-64
2015
Synechococcus elongatus (Q31MN3), Synechococcus elongatus PCC7942 (Q31MN3)
Manually annotated by BRENDA team
Unissa, A.N.; Doss C, G.P.; Kumar, T.; Swathi, S.; Lakshmi, A.R.; Hanna, L.E.
Analysis of interactions of clinical mutants of catalase-peroxidase (KatG) responsible for isoniazid resistance in Mycobacterium tuberculosis with derivatives of isoniazid
J. Glob. Antimicrob. Resist.
11
57-67
2017
Mycobacterium tuberculosis
Manually annotated by BRENDA team
Philibert, T.; Rao, Z.; Yang, T.; Zhou, J.; Huang, G.; Irene, K.; Samuel, N.
Heterologous expression and characterization of a new heme-catalase in Bacillus subtilis 168
J. Ind. Microbiol. Biotechnol.
43
729-740
2016
Bacillus pumilus (A0A143G976), Bacillus pumilus, Bacillus pumilus ML 413 (A0A143G976)
Manually annotated by BRENDA team
Pimentel, A.L.; de Lima Scodro, R.B.; Caleffi-Ferracioli, K.R.; Siqueira, V.L.; Campanerut-Sa, P.A.; Lopes, L.D.; de Almeida, A.L.; Cardoso, R.F.; Seixas, F.A.
Mutations in catalase-peroxidase KatG from isoniazid resistant Mycobacterium tuberculosis clinical isolates insights from molecular dynamics simulations
J. Mol. Model.
23
121
2017
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5)
Manually annotated by BRENDA team
Vidossich, P.; Loewen, P.C.; Carpena, X.; Fiorin, G.; Fita, I.; Rovira, C.
Binding of the antitubercular pro-drug isoniazid in the heme access channel of catalase-peroxidase (KatG). A combined structural and metadynamics investigation
J. Phys. Chem. B
118
2924-2931
2014
Burkholderia pseudomallei (Q3JNW6), Burkholderia pseudomallei 1710b (Q3JNW6)
Manually annotated by BRENDA team
Gao, S.; Gold, S.E.; Glenn, A.E.
Characterization of two catalase-peroxidase encoding genes in Fusarium verticillioides reveals differential responses to in vitro versus in planta oxidative challenges
Mol. Plant Pathol.
19
1127-1139
2017
Fusarium verticillioides, Fusarium verticillioides JFL A00999, Fusarium verticillioides M3125
Manually annotated by BRENDA team
Loewen, P.; Villanueva, J.; Switala, J.; Donald, L.; Ivancich, A.
Unprecedented access of phenolic substrates to the heme active site of a catalase Substrate binding and peroxidase-like reactivity of Bacillus pumilus catalase monitored by X-ray crystallography and EPR spectroscopy
Proteins
83
853-866
2015
Bacillus pumilus
Manually annotated by BRENDA team
Fita, I.; Carpena, X.; Loewen, P.
Chapter 7 Catalase-peroxidase (KatG) structure and function
RSC Metallobiol.
2016
135-155
2016
Haloarcula marismortui
-
Manually annotated by BRENDA team
Purka, P.; Ihsanawat, I.; Natalia, D.; Syah, Y.; Retnoningrum, D.; Kusuma, H.
Mutation of katG in a clinical isolate of Mycobacterium tuberculosis Effects on catalase-peroxidase for isoniazid activation
Ukr. Biochem. J.
88
71-81
2016
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis H37Rv (P9WIE5)
-
Manually annotated by BRENDA team
Vega-Garcia, V.; Diaz-Vilchis, A.; Saucedo-Vazquez, J.P.; Solano-Peralta, A.; Rudino-Pinera, E.; Hansberg, W.
Structure, kinetics, molecular and redox properties of a cytosolic and developmentally regulated fungal catalase-peroxidase
Arch. Biochem. Biophys.
640
17-26
2018
Neurospora crassa (Q8X182), Neurospora crassa, Neurospora crassa CBS 708.71 (Q8X182), Neurospora crassa 74-OR23-1A (Q8X182), Neurospora crassa DSM 1257 (Q8X182), Neurospora crassa ATCC 24698 (Q8X182), Neurospora crassa FGSC 987 (Q8X182)
Manually annotated by BRENDA team
Struharnanska, E.; Chovanova, M.; Rybecka, S.; Mikulasova, M.; Levarski, Z.; Zamocky, M.; Stuchlik, S.; Turna, J.
Evaluation of thermostable catalase-peroxidase AfKatG supplementation on toxicity of residual hydrogen peroxide in cultivation media of lactic acid bacteria from starter cultures
Gen. Physiol. Biophys.
38
455-460
2019
Archaeoglobus fulgidus (O28050), Archaeoglobus fulgidus NBRC 100126 (O28050), Archaeoglobus fulgidus ATCC 49558 (O28050), Archaeoglobus fulgidus VC-16 (O28050), Archaeoglobus fulgidus JCM 9628 (O28050)
Manually annotated by BRENDA team
Kamlarova, A.; Chovanova, K.; Zamocky, M.
Peculiar genes for thermostable bifunctional catalase-peroxidases in Chaetomium thermophilum and their molecular evolution
Gene
666
83-91
2018
Thermochaetoides dissita (A0A223PYP9)
Manually annotated by BRENDA team
Unissa, A.N.; Doss C, G.P.; Kumar, T.; Sukumar, S.; Lakshmi, A.R.; Hanna, L.E.
Significance of catalase-peroxidase (KatG) mutations in mediating isoniazid resistance in clinical strains of Mycobacterium tuberculosis
J. Glob. Antimicrob. Resist.
15
111-120
2018
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5), Mycobacterium tuberculosis ATCC 25618 (P9WIE5)
Manually annotated by BRENDA team
Purkan, P.; Ihsanawati, I.; Natalia, D.; Syah, Y.; Retnoningrum, D.; Siswanto, I.
Molecular analysis of katG encoding catalase-peroxidase from clinical isolate of isoniazid-resistant Mycobacterium tuberculosis
J. Med. Life
11
160-167
2018
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5), Mycobacterium tuberculosis ATCC 25618 (P9WIE5)
Manually annotated by BRENDA team
Gao, S.; Gold, S.; Glenn, A.
Characterization of two catalase-peroxidase-encoding genes in Fusarium verticillioides reveals differential responses to inxa0vitro versus inxa0planta oxidative challenges
Mol. Plant Pathol.
19
1127-1139
2018
Fusarium verticillioides (W7MLS8), Fusarium verticillioides (W7NEP8), Fusarium verticillioides, Fusarium verticillioides M3125 (W7MLS8), Fusarium verticillioides M3125 (W7NEP8), Fusarium verticillioides FGSC 7600 (W7MLS8), Fusarium verticillioides FGSC 7600 (W7NEP8)
Manually annotated by BRENDA team
Munir, A.; Wilson, M.T.; Hardwick, S.W.; Chirgadze, D.Y.; Worrall, J.A.R.; Blundell, T.L.; Chaplin, A.K.
Using cryo-EM to understand antimycobacterial resistance in the catalase-peroxidase (KatG) from Mycobacterium tuberculosis
Structure
29
899-912.e4
2021
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5), Mycobacterium tuberculosis ATCC 25618 (P9WIE5)
Manually annotated by BRENDA team
Marney, M.W.; Metzger, R.P.; Hecht, D.; Valafar, F.
Modeling the structural origins of drug resistance to isoniazid via key mutations in Mycobacterium tuberculosis catalase-peroxidase, KatG
Tuberculosis
108
155-162
2018
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5), Mycobacterium tuberculosis ATCC 25618 (P9WIE5)
Manually annotated by BRENDA team
Reyes, Y.I.A.; Janairo, G.C.; Franco, F.C.
Theoretical insights on the binding of isoniazid to the active site residues of Mycobacterium tuberculosis catalase-peroxidase
Tuberculosis
114
61-68
2019
Mycobacterium tuberculosis (P9WIE5), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WIE5), Mycobacterium tuberculosis ATCC 25618 (P9WIE5)
Manually annotated by BRENDA team