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1.11.1.22: hydroperoxy fatty acid reductase

This is an abbreviated version!
For detailed information about hydroperoxy fatty acid reductase, go to the full flat file.

Word Map on EC 1.11.1.22

Reaction

a hydroperoxy fatty acid
+
NADPH
+
H+
=
a hydroxy fatty acid
+
NADP+
+
H2O

Synonyms

glutathione peroxidase-like protein, glutathione peroxidase-like protein-1, glutathione peroxidase-like protein-2, Gpx-1, GPx-2, slr1171, slr1992

ECTree

     1 Oxidoreductases
         1.11 Acting on a peroxide as acceptor
             1.11.1 Peroxidases
                1.11.1.22 hydroperoxy fatty acid reductase

Inhibitors

Inhibitors on EC 1.11.1.22 - hydroperoxy fatty acid reductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ag+
-
complete inhibition at 1 mM
Cu2+
-
complete inhibition at 1 mM
Mercaptosuccinate
-
-
N-ethylmaleimide
-
60% inhibition of isoform Gpx-1 at 1 mM
p-chloromercuribenzoate
-
30% inhibition of isoform Gpx-1 at 0.3 mM
additional information
-
not inhibited by 1 mM cyanide and 1 mM azide
-