1.11.1.6: catalase
This is an abbreviated version!
For detailed information about catalase, go to the full flat file.
Word Map on EC 1.11.1.6
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1.11.1.6
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dismutase
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sod
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malondialdehyde
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gsh
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ascorbate
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necrosis
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thiobarbituric
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erythrocyte
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wistar
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endothelial
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xanthine
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glutathione-s-transferase
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artery
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cholesterol
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s-transferase
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caspase-3
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albino
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chlorophyll
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copper
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heme
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creatinine
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myeloperoxidase
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tnf
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anti-oxidant
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peroxisomal
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gsh-px
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tbars
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biotechnology
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streptozotocin
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agriculture
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ache
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analysis
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comet
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hydroperoxide
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hepatoprotective
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nephrotoxicity
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neuroprotective
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sacrificed
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mannitol
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defenses
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h2o2-induced
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urease
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cadmium
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alt
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industry
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hepatotoxicity
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degradation
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ischemia
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diagnostics
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gill
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pro-oxidant
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synthesis
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alpha-tocopherol
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acetylcholinesterase
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aquatic
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medicine
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reperfusion
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polyphenols
-
energy production
- 1.11.1.6
- dismutase
- sod
- malondialdehyde
- gsh
- ascorbate
- necrosis
-
thiobarbituric
- erythrocyte
- wistar
- endothelial
- xanthine
- glutathione-s-transferase
- artery
- cholesterol
- s-transferase
- caspase-3
-
albino
- chlorophyll
- copper
- heme
- creatinine
- myeloperoxidase
- tnf
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anti-oxidant
- peroxisomal
- gsh-px
-
tbars
- biotechnology
- streptozotocin
- agriculture
-
ache
- analysis
- comet
- hydroperoxide
-
hepatoprotective
-
nephrotoxicity
-
neuroprotective
-
sacrificed
- mannitol
-
defenses
-
h2o2-induced
- urease
- cadmium
-
alt
- industry
-
hepatotoxicity
- degradation
- ischemia
- diagnostics
- gill
-
pro-oxidant
- synthesis
- alpha-tocopherol
- acetylcholinesterase
-
aquatic
- medicine
-
reperfusion
- polyphenols
- energy production
Reaction
2 H2O2
=
Synonyms
Ab-catalase, BNC, caperase, CAT, CAT-1, CAT-A, CAT-P, Cat1.4, CatA, catalase, catalase A, catalase C, catalase form III, catalase P, catalase-1, catalase-A, catalase-peroxidase, catalase-phenol oxidase, CatB, CATC, CatF, CatG, CatP, CATPO, CcmC, CP, equilase, H2O2:H2O2 oxidoreductase, haem catalase, HPI-A, HPI-B, HPII, HTHP, hydrogen peroxide oxidoreductase, KAT, Kat E catalase, KatA, KatB, KatC, KatP, KpA, manganese catalase, More, optidase, PktA, polyethylene glycol-catalase, tyrosine-coordinated heme protein, VktA
ECTree
1.11.1.6 catalaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.11.1.6 - catalase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1-H-pyrrol-2-carbohydrazide
?
-
analysis of association and dissociation rate constants
-
-
?
benzoic hydrazide
?
-
analysis of association and dissociation rate constants
-
-
?
furoic hydrazide
?
-
analysis of association and dissociation rate constants
-
-
?
isonicotinic hydrazide
?
-
antituberculosis drug, bactericidal function neeeds activation by bifunctional catalase-peroxidase KatG to produce an acyl-NAD adduct. Substrate binds with high affinity to a small portion of ferric enzyme in a six-coordinate heme iron form
-
-
?
nicotinic hydrazide
?
-
analysis of association and dissociation rate constants
-
-
?
picolinic hydrazide
?
-
analysis of association and dissociation rate constants
-
-
?
reduced cytochrome c + H2O2
oxidized cytochrome c + H2O
-
-
-
?
2 H2O2
O2 + 2 H2O
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via Compound I and Compound II intermediates
-
-
?
2 H2O2
O2 + 2 H2O
Mycothermus thermophilus ATCC 16454
-
via Compound I and Compound II intermediates
-
-
?
2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O2
? + H2O
-
only isoenzyme I has peroxidase activity
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?
2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O2
? + H2O
-
only isoenzyme I has peroxidase activity
-
?
2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O2
? + H2O
-
-
-
?
2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) + H2O2
? + H2O
-
-
-
?
beta-(3,4-dihydroxyphenyl)-L-alanine + H2O2
? + H2O
Kloeckera sp. 2201
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low activity
-
?
H2O2
O2 + H2O
-
two monofunctional, one bifunctional catalase-peroxidase
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?
H2O2
O2 + H2O
-
two monofunctional, one bifunctional catalase-peroxidase
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?
H2O2
O2 + H2O
-
detoxification enzyme, enzyme protects the cell against high concentrations of peroxide
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-
?
H2O2
O2 + H2O
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enzyme is responsible for prevention of dehydration-related oxidative damage during seed desiccation, H2O2 may play a role for enzyme expression regulation and in the transduction pathway
-
-
?
H2O2
O2 + H2O
-
enzyme is responsible for the protection of the Helicobacter pylori cells against phagocyte attack in the gastric mucosa by disumtation of H2O2
-
-
?
H2O2
O2 + H2O
-
detoxification and protection enzyme
-
-
?
H2O2
O2 + H2O
-
regulator of H2O2-levels or protective function for hemoglobin or other SH-proteins
-
?
H2O2
O2 + H2O
two monofunctional catalases, Cat-1 and Cat-3, one catalase-peroxidase enzyme, Cat-2
-
?
H2O2
O2 + H2O
fungal enzyme interacts with the host, enzyme plays a role in the defense of the organism against oxygen-dependent killing mechanisms
-
-
?
H2O2
O2 + H2O
fungal enzyme interacts with the host, enzyme plays a role in the defense of the organism against oxygen-dependent killing mechanisms
-
-
?
H2O2
O2 + H2O
-
detoxification enzyme, enzyme is naturally adapted to the cold climate of the arctic tundra
-
-
?
H2O2
O2 + H2O
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detoxification enzyme, enzyme is naturally adapted to the cold climate of the arctic tundra
-
-
?
H2O2
O2 + H2O
-
one catalase-peroxidase, one catalase enzyme
-
?
H2O2
O2 + H2O
-
KatA catalase important for resistance of planctonic and biofilm cells to H2O2
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?
H2O2
O2 + H2O
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essential for optimal resistance to H2O2. KatB was not produced during the normal growth cycle. Catalase activity is greater in nonmucoid than in mucoid, alginate-producing organisms. When exposed to hydrogen peroxide and, to a greater extent, paraquat, total catalase activity was elevated 7fold to 16fold, respectively
-
-
?
H2O2
O2 + H2O
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H2O2 decomposition is accompanied by enzyme inactivation which can be minimized in vitro by immobilization of the enzyme
-
-
?
H2O2
O2 + H2O
-
H2O2 decomposition is accompanied by enzyme inactivation which can be minimized in vitro by immobilization of the enzyme
-
-
?
H2O2 + methanol
formaldehyde + H2O
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peroxidase activity
-
-
?
methanol + H2O2
formaldehyde + ?
Kloeckera sp.
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only in the presence of glucose and glucose oxidase
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?
methanol + H2O2
formaldehyde + ?
Kloeckera sp. 2201
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only in the presence of glucose and glucose oxidase
-
?
o-methoxyphenol + H2O2
? + H2O
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only isoenzyme I has peroxidase activity
-
?
o-methoxyphenol + H2O2
? + H2O
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only isoenzyme I has peroxidase activity
-
?
o-methoxyphenol + H2O2
? + H2O
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i.e. guaiacol
-
?
additional information
?
-
no substrate: o-phenylenediamine. The purified catalase is not reduced by sodium dithionite
-
-
?
additional information
?
-
-
enzyme also shows alkaline peroxidase activity, which is much lower than the catalase activity, no peroxidase activity with 3-aminophenol, 2,4,6-trichlorophenol, and 3-nitrophenol
-
-
?
additional information
?
-
-
BNC does not show any peroxidatic activity with 4-aminoantipyrine or pyrogallol as substrate
-
-
?
additional information
?
-
-
enzyme also shows alkaline peroxidase activity, which is much lower than the catalase activity, no peroxidase activity with 3-aminophenol, 2,4,6-trichlorophenol, and 3-nitrophenol
-
-
?
additional information
?
-
-
BNC does not show any peroxidatic activity with 4-aminoantipyrine or pyrogallol as substrate
-
-
?
additional information
?
-
-
the enzyme does not interact with Brij 35 micelles, enzyme exhibits superactivity in the reverse micells formed by 0.1 M Brij 30 in heptane, isooctane, and dodecane, but not in decaline
-
-
?
additional information
?
-
-
adenine deaminase, EC 3.5.4.2, from the amidohydrolase superfamily of enzymes catalyzes the conversion of adenine to hypoxanthine and ammonia. But it also catalyzes the catalase reaction converting H2O2 to H2O and O2. [MnII/MnII]-ADEec is active as a deaminase but not as a catalase. In contrast, [FeII/FeII]-ADEec catalyzes both reactions
-
-
?
additional information
?
-
-
regulation of enzyme expression and activity by drying occurs on transcriptional level, increase in enzyme activity during drying is associated with an decrease of H2O2 level and lipid peroxidation
-
-
?
additional information
?
-
-
the enzyme contains a unique tetra-lysine motif at the C-terminus which probably is required for interaction with protein KapA
-
-
?
additional information
?
-
-
the enzyme has negligible inhibitory effects on endothelium-dependent relaxations in mouse isolated aorta and small mesenteric artery which are not caused by H2O2, endothelium-independent relaxations are caused by H2O2 and are abolished by the enzyme, overview
-
-
?
additional information
?
-
-
the bifunctional catalase with phenol oxidase activity catalyses the decomposition of hydrogen peroxide into oxygen and water and also oxidizes various phenolic compounds
-
-
?
additional information
?
-
Mycothermus thermophilus ATCC 16454
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the bifunctional catalase with phenol oxidase activity catalyses the decomposition of hydrogen peroxide into oxygen and water and also oxidizes various phenolic compounds
-
-
?
additional information
?
-
bifunctional aa3 cytochrome c oxidase, CcO, possesses a peroxidase and a catalase activity
-
-
?
additional information
?
-
-
bifunctional aa3 cytochrome c oxidase, CcO, possesses a peroxidase and a catalase activity
-
-
?
additional information
?
-
bifunctional aa3 cytochrome c oxidase, CcO, possesses a peroxidase and a catalase activity
-
-
?
additional information
?
-
-
peroxidase and catalase activities are involved in direct adventitious shoot formation induced by thidiazuron in zygotic embryos
-
-
?
additional information
?
-
-
CcmC is a key determinant for cytochrome c biogenesis, pyoverdine maturation, and expression of some quorum sensing-regulated traits
-
-
?
additional information
?
-
-
the enzyme is involved in protection against peroxides and oxidative DNA damage, it is downregulated in biofilm cultures of Pseudomonas aeruginosa, that display up to a 105fold increase in mutability compared with planktonic cultures
-
-
?
additional information
?
-
-
no detectable peroxidase activity
-
-
?
additional information
?
-
-
enzyme is easiliy reduced by dithionite, no peroxidase activity with o-dianisidine and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)
-
-
?
additional information
?
-
-
2 enzymes TvC-I and TvC-II do not show peroxidase ctivity
-
-
?
