1.12.99.6: hydrogenase (acceptor)

This is an abbreviated version!
For detailed information about hydrogenase (acceptor), go to the full flat file.

Reaction

Synonyms

ECH, Ech hydrogenase, EchA, EchB, EchD, EchE, EchF, endo-hydrogenase, energy-converting hydrogenase, exo-hydrogenase, F420-reducing [NiFe] hydrogenase, factor420 hydrogenase, Fe-hydrogenase, Fe-only hydrogenase, ferredoxin hydrogenase, H2 producing hydrogenase [ambiguous], H2-sensing [NiFe] hydrogenase, Hfs, Hmd, HoxEFUYH type [NiFe] hydrogenase, HoxG, HupB, HupL, HupS, hupSLW, Hya, HyaA, HyaB, Hyb, HybA, HyC, HycE, Hyd X, Hyd-1, Hyd-2, Hyd-3, Hyd-4, HYD1, hydA, HydA1, HydA2, HydB, hydrogen dehydrogenase, hydrogen uptake hydrogenase, hydrogen-forming methylenetetrahydromethanopterin dehydrogenase, hydrogen-lyase, hydrogen-lyase [ambiguous], hydrogen:ferredoxin oxidoreductase, hydrogen:methylviologen oxidoreductase, hydrogenase (ferredoxin), hydrogenase 1, hydrogenase 2, hydrogenase 3, hydrogenase I (bidirectional), hydrogenase II, hydrogenase II (uptake), hydrogenase-1, hydrogenase-2, hydrogenase-Fe-S, hydrogenases Hyd-1, hydrogenases Hyd-2, hydrogenlyase [ambiguous], hyf, HyhL, HynSL, HynSL hydrogenase, Hyq, iron-sulfur-cluster-free hydrogenase, Mbh, membrane-bound [NiFe]-hydrogenase, methyl viologen-reducing hydrogenase, methylviologen hydrogenase, Ni-Fe hydrogenase, nickel-iron hydrogenase, NiFe hydrogenase, NiFe(Se) hydrogenase, NiFe-hydrogenase, NIFeSe-hydrogenase, regulatory hydrogenase, respiratory hydrogenase, SHI, uptake hydrogenase, uptake hydrogenase [ambiguous], uptake [NiFe] hydrogenase:, uptake [NiFe]-hydrogenase, [FeFe] hydrogenase, [FeFe]-H2ase, [FeFe]-hydrogenase, [FeFe]H2ase, [Fe] hydrogenase, [Fe]-hydA, [Fe]-hydrogenase, [Ni-Fe] hydrogenase, [NiFeSe]-hydrogenase, [NiFe] hydrogenase, [NiFe]-hydrogenase, [NiFe]-hydrogenase 2, [NiFe]-hydrogenase-2, [NiFe]H2ase, [NiFe]hydrogenase

ECTree

     1 Oxidoreductases

         1.12 Acting on hydrogen as donor

             1.12.99 With unknown physiological acceptors

                1.12.99.6 hydrogenase (acceptor)

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Results	in table
25	Activating Compound
6379	AA Sequence
7	Application
1	CAS Registry Number
28	Cloned(Commentary)
24	Cofactor
11	Crystallization (Commentary)
5	Expression
19	General Information
12	General Stability
67	Inhibitors
3	kcat/KM [mM/s]
7	Ki Value [mM]
35	KM Value [mM]
64	Localization
120	Metals/Ions
75	Molecular Weight [Da]
60	Natural Substrates/ Products (Substrates)
549	Organism
10	Oxidation Stability
5	Pathway
182	PDB ID
26	pH Optimum
6	pH Range
3	pH Stability
8	pI Value
61	Protein Variants
65	Purification (Commentary)
7	Reaction
3	Reaction Type
274	Reference
12	Source Tissue
47	Specific Activity [micromol/min/mg]
10	Storage Stability
242	Substrates and Products (Substrate)
53	Subunits
524	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
2	Temperature Range [°C]
22	Temperature Stability [°C]
9	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.12.99.6 - hydrogenase (acceptor)

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

H2 + acceptor

acceptor-H2

2 entries

H2 + acceptor

acceptorH2

2 entries

H2 + acceptor

H+ + reduced acceptor

48 entries

H2 + acceptor

reduced acceptor

3 entries

H2 + methylene blue

reduced methylene blue

Escherichia coli

-

-

742265

-

-

?

H2 + NADPH

NADP + H+

2 entries

H2 + acceptor

acceptor-H2

Allochromatium vinosum

-

-

658987

-

-

?

H2 + acceptor

acceptor-H2

Megalodesulfovibrio gigas

Q7WT77, Q7WT78, Q7WT79, Q7WT80, Q7WT81, Q7WT82

-

657739

-

-

?

H2 + acceptor

acceptorH2

Allochromatium vinosum

-

-

658082

-

-

?

H2 + acceptor

acceptorH2

Gloeothece sp.

Q841J7, Q841J8

-

659887

-

-

?

H2 + acceptor

H+ + reduced acceptor

Bradyrhizobium sp.

-

inactivation of hydrogenase genes impairs bacterial nitrogenase activity in Bradyrhizobium sp. (Vigna) and has an effect on total nitrogen content of the symbiotic plant partner, Vigna unguiculata. Hydrogenase activity might be necessary for optimal levels of nitrogenase activity in Bradyrhizobium sp. (Vigna) bacteroids

671432

-

-

?

H2 + acceptor

H+ + reduced acceptor

Candidatus Atelocyanobacterium thalassa

D3EMX6

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Clostridium pasteurianum

-

reaction mechanism

439644

-

-

?

H2 + acceptor

H+ + reduced acceptor

Clostridium pasteurianum

-

2 different enzymes, hydrogenase I and II

439627

-

439627

r

H2 + acceptor

H+ + reduced acceptor

Crocosphaera subtropica ATCC 51142

B1WTU9

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Crocosphaera subtropica ATCC 51142 CCY 0110

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Crocosphaera subtropica ATCC 51142 PCC 7424

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Crocosphaera subtropica ATCC 51142 PCC 7425b

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Crocosphaera subtropica ATCC 51142 PCC 7822

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Crocosphaera subtropica ATCC 51142 PCC 8801

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Crocosphaera subtropica ATCC 51142 PCC 8802

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Cronbergia siamensis SAG 11.82

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Cronbergia siamensis SAG 11.82 TISTR 8012

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Cylindrospermopsis raciborskii

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Cylindrospermopsis raciborskii CS-505

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Desulfovibrio desulfuricans

-

reaction mechanism

439644

-

-

?

H2 + acceptor

H+ + reduced acceptor

Desulfovibrio vulgaris

-

reaction mechanism

439637, 439645

-

-

?

H2 + acceptor

H+ + reduced acceptor

Desulfovibrio vulgaris Miyazaki F

-

reaction mechanism

439637, 439645

-

-

?

H2 + acceptor

H+ + reduced acceptor

Gloeocapsa alpicola

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Gloeocapsa alpicola CALU 743

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Limnospira maxima

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Limnospira maxima CS-328

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Limnospira maxima FACHBSM

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Lyngbya aestuarii

Q2EJS7

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Lyngbya aestuarii CCY 9616

Q2EJS7

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Lyngbya majuscula

Q846P6

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Lyngbya majuscula

-

-

712029

-

-

?

H2 + acceptor

H+ + reduced acceptor

Lyngbya majuscula CCAP 1446/4

-

-

712029

-

-

?

H2 + acceptor

H+ + reduced acceptor

Lyngbya majuscula CCAP 1446/4

Q846P6

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Megalodesulfovibrio gigas

-

reaction mechanism

439638

-

-

?

H2 + acceptor

H+ + reduced acceptor

Methanosarcina barkeri

-

ferredoxin acts as physiological electron donor

439643

-

-

?

H2 + acceptor

H+ + reduced acceptor

Methanosarcina barkeri Fusaro / DSM 804

-

ferredoxin acts as physiological electron donor

439643

-

-

?

H2 + acceptor

H+ + reduced acceptor

Microcystis aeruginosa

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Microcystis aeruginosa NIES-843

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Nostoc punctiforme

-

-

712029

-

-

?

H2 + acceptor

H+ + reduced acceptor

Nostoc sp.

-

-

712029

-

-

?

H2 + acceptor

H+ + reduced acceptor

Nostoc sp.

Q3C1T8, Q8YZ11

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Nostoc sp. PCC 7120

-

-

712029

-

-

?

H2 + acceptor

H+ + reduced acceptor

Nostoc sp. PCC 7120

Q8YZ11

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Nostoc sp. PCC 7422

Q3C1T8

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Prochlorothrix hollandica

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Pyrococcus furiosus

-

ferredoxin acts as physiological electron donor

439632

-

-

?

H2 + acceptor

H+ + reduced acceptor

Raphidiopsis brookii

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Raphidiopsis brookii D9

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Synechococcus elongatus

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Synechococcus elongatus PCC 7942

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Synechocystis sp.

-

-

713374

-

-

?

H2 + acceptor

H+ + reduced acceptor

Trichormus variabilis

Q9ZAK2

-

713374

-

-

?

H2 + acceptor

reduced acceptor

Clostridium pasteurianum

-

-

742652

-

-

?

H2 + acceptor

reduced acceptor

Escherichia coli

P69741

the periplasmic-facing membrane-bound complex functions as a proton pump to convert energy from hydrogen (H2) oxidation into a proton gradient

764102

-

-

?

H2 + acceptor

reduced acceptor

Escherichia coli K12

P69741

the periplasmic-facing membrane-bound complex functions as a proton pump to convert energy from hydrogen (H2) oxidation into a proton gradient

764102

-

-

?

H2 + NADPH

NADP + H+

Pyrococcus furiosus

-

-

743732

-

-

?

H2 + NADPH

NADP + H+

Pyrococcus furiosus MW0430

-

-

743732

-

-

?