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1,2,3-trihydroxybenzene + O2
2-hydroxymuconate
-
-
-
-
?
1,2,4-benzenetriol + O2
?
-
52% activity compared to catechol
-
-
?
2,3-dihydroxybenzoic acid + O2
?
-
-
-
?
3,4,5,6-tetrachlorocatechol + O2
?
-
-
-
?
3,4-dihydroxybenzoic acid + O2
?
3,4-dimethylcatechol + O2
3,4-dimethyl-cis,cis-muconate
3,5-dichlorocatechol + O2
(2E,4E)-2,4-dichlorohexa-2,4-dienedioate
3,5-dichlorocatechol + O2
?
3,5-dimethylcatechol + O2
3,5-dimethyl-cis,cis-muconate
3-butylcatechol + O2
2-butylhexa-2,4-dienedioic acid
-
weak activity
-
-
?
3-chloro-5-methylcatechol + O2
2-chloro-4-methylhexa-2,4-dienedioate
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
3-chlorocatechol + O2
?
-
-
-
-
?
3-chloropyrocatechol + O2
?
3-ethylcatechol + O2
2-ethyl-cis,cis-muconic acid
3-isopropylcatechol + O2
2-isopropyl-cis,cis-muconate
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
3-methylcatechol + O2
2-methyl-cis,cis-muconate
3-methylpyrocatechol + O2
2,3,5-trimethyl-cis-cis-muconate
3-methylthiocatechol + O2
2-methylthio-cis,cis-muconate
-
very poor substrate
-
-
?
4,5-dichlorocatechol + O2
?
4,5-difluorocatechol + O2
3,4-difluoro-cis-cis-muconate
-
-
-
-
?
4-bromocatechol + O2
3-bromo-cis-cis-muconate
4-chloro-5-fluorocatechol + O2
?
-
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
4-chlorocatechol + O2
4-chloro-cis,cis-muconate
4-chlorocatechol + O2
4-chlorocis,cis-muconate
-
-
-
-
?
4-ethylcatechol + O2
4-ethyl-cis-cis-muconate
-
42% of activity with catechol
-
-
?
4-fluorocatechol + O2
3-fluoro-cis,cis-muconate
4-fluorocatechol + O2
4-fluoro-cis,cis-muconate
-
65% of activity with catechol
-
-
?
4-hydroxybenzoic acid + O2
?
4-iso-propylcatechol + O2
4-isopropyl-cis,cis-muconate
-
23% of activity with catechol
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
4-methylcatechol + O2
3-methyl-cis,cis-hexadienedioate
-
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
4-methylcatechol + O2
3-methylhexa-2,4-dienedioate
4-methylcatechol + O2
4-methyl-cis,cis-muconate
4-methylpyrocatechol + O2
2,4,5-trimethyl-cis-cis-muconate
4-n-propylcatechol + O2
4-n-propyl-cis,cis-muconate
-
17% of activity with catechol
-
-
?
4-nitrocatechol + O2
?
-
80% activity compared to catechol
-
-
?
4-tert-butylcatechol + O2
?
benzene-1,2,4-triol + O2
?
benzoate + O2
?
-
-
-
-
?
benzoic acid + O2
?
-
-
-
?
catechol + O2
cis,cis-muconate
catechol + O2
cis,cis-muconic acid
catechol + O2
cis-cis muconate
assay at pH 8.0, 30°C
-
-
?
hydroxyquinol + O2
?
i.e. 1,2,4-trihydroxy benzene
-
-
?
hydroxyquinol + O2
maleylacetic acid
protocatechuate + O2
?
i.e. 3,4-dihydroxybenzoate
-
-
?
pyrocatechol + O2
2,5-dimethyl-cis-cis-muconate
pyrogallol + O2
alpha-hydroxymuconic acid
tetrachlorocatechol + O2
cis,cis-tetrachloromuconic acid
-
-
-
-
?
additional information
?
-
3,4-dihydroxybenzoic acid + O2
?
-
-
-
?
3,4-dihydroxybenzoic acid + O2
?
-
-
-
?
3,4-dimethylcatechol + O2
3,4-dimethyl-cis,cis-muconate
-
21% of activity with catechol
-
-
?
3,4-dimethylcatechol + O2
3,4-dimethyl-cis,cis-muconate
-
21% of activity with catechol
-
-
?
3,5-dichlorocatechol + O2
(2E,4E)-2,4-dichlorohexa-2,4-dienedioate
-
reaction catalyzed by catechol 1,2-dioxygenase type II
-
-
?
3,5-dichlorocatechol + O2
(2E,4E)-2,4-dichlorohexa-2,4-dienedioate
-
reaction catalyzed by catechol 1,2-dioxygenase type II
-
-
?
3,5-dichlorocatechol + O2
?
-
-
-
?
3,5-dichlorocatechol + O2
?
99.35% compared to the activity with catechol
-
-
?
3,5-dichlorocatechol + O2
?
99.35% compared to the activity with catechol
-
-
?
3,5-dimethylcatechol + O2
3,5-dimethyl-cis,cis-muconate
-
36% of activity with catechol
-
-
?
3,5-dimethylcatechol + O2
3,5-dimethyl-cis,cis-muconate
-
36% of activity with catechol
-
-
?
3-chloro-5-methylcatechol + O2
2-chloro-4-methylhexa-2,4-dienedioate
-
reaction catalyzed by catechol 1,2-dioxygenase type II
-
-
?
3-chloro-5-methylcatechol + O2
2-chloro-4-methylhexa-2,4-dienedioate
-
reaction catalyzed by catechol 1,2-dioxygenase type II
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
CatA1: 4.4% of the activity with catechol
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
CatA1: 4.4% of the activity with catechol
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
-
-
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
-
-
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
-
pyrocatechase II, in 3-chlorobenzoate-grown cells
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
-
pyrocatechase II, in 3-chlorobenzoate-grown cells
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
1.7% activity compared to catechol
-
-
?
3-chlorocatechol + O2
2-chloro-cis,cis-muconate
1.7% activity compared to catechol
-
-
?
3-chloropyrocatechol + O2
?
-
weak activity
-
-
?
3-chloropyrocatechol + O2
?
-
-
-
-
?
3-chloropyrocatechol + O2
?
-
-
-
-
?
3-chloropyrocatechol + O2
?
-
-
-
-
?
3-chloropyrocatechol + O2
?
-
-
-
-
?
3-ethylcatechol + O2
2-ethyl-cis,cis-muconic acid
-
-
-
-
?
3-ethylcatechol + O2
2-ethyl-cis,cis-muconic acid
-
poor substrate
-
?
3-isopropylcatechol + O2
2-isopropyl-cis,cis-muconate
-
-
-
-
?
3-isopropylcatechol + O2
2-isopropyl-cis,cis-muconate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
the enzyme preferentially recognizes 4-substituted over 3-substituted catechols
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
the enzyme preferentially recognizes 4-substituted over 3-substituted catechols
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
poor substrate
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
poor substrate
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
poor substrate
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
poor substrate
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
poor substrate
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
poor substrate
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
104% activity compared to catechol
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
104% activity compared to catechol
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
-
-
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
117.4% compared to the activity with catechol
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
9.9% compared to the activity with catechol
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
9.9% compared to the activity with catechol
-
-
?
3-methylcatechol + O2
(2Z,4Z)-2-methylhexa-2,4-dienedioate
117.4% compared to the activity with catechol
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
-
-
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
-
10% of the activity with catechol
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
-
10% of the activity with catechol
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
-
64% of activity with catechol
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
-
64% of activity with catechol
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
-
enzyme from aniline-grown cells: 74% of the activity with catechol, enzyme from L-malate-grown cells: 71% of the activity with catechol
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
11.6% of the activity with catechol
-
-
?
3-methylcatechol + O2
2-methyl-cis,cis-muconate
11.6% of the activity with catechol
-
-
?
3-methylcatechol + O2
?
-
-
-
-
?
3-methylcatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
3-methylcatechol + O2
?
-
-
-
-
?
3-methylcatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
3-methylcatechol + O2
?
-
2% activity compared to catechol
-
-
?
3-methylcatechol + O2
?
-
assay at 60°C, pH 7.0
-
-
?
3-methylcatechol + O2
?
-
assay at 60°C, pH 7.0
-
-
?
3-methylcatechol + O2
?
-
-
-
-
?
3-methylcatechol + O2
?
-
-
-
-
?
3-methylpyrocatechol + O2
2,3,5-trimethyl-cis-cis-muconate
-
-
-
-
?
3-methylpyrocatechol + O2
2,3,5-trimethyl-cis-cis-muconate
-
-
-
-
?
3-methylpyrocatechol + O2
2,3,5-trimethyl-cis-cis-muconate
-
-
-
-
?
3-methylpyrocatechol + O2
2,3,5-trimethyl-cis-cis-muconate
-
-
-
-
?
3-methylpyrocatechol + O2
2,3,5-trimethyl-cis-cis-muconate
-
-
-
-
?
4,5-dichlorocatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
4,5-dichlorocatechol + O2
?
the enzyme possesses only a quite rare capability to process 4,5-dichlorocatechol
-
-
?
4,5-dichlorocatechol + O2
?
the enzyme possesses only a quite rare capability to process 4,5-dichlorocatechol
-
-
?
4,5-dichlorocatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
4,5-dichlorocatechol + O2
?
-
-
-
?
4-bromocatechol + O2
3-bromo-cis-cis-muconate
-
-
-
-
?
4-bromocatechol + O2
3-bromo-cis-cis-muconate
-
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
the enzyme preferentially recognizes 4-substituted over 3-substituted catechols
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
the enzyme preferentially recognizes 4-substituted over 3-substituted catechols
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
CatA1: 18.1% of the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
CatA2: 2.5% of the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
CatA1: 18.1% of the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
CatA2: 2.5% of the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
11% of the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
11% of the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
poor substrate
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
pyrocatechase II, in 3-chlorobenzoate-grown cells
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
-
pyrocatechase II, in 3-chlorobenzoate-grown cells
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
2.7% activity compared to catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
2.7% activity compared to catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
3.3% compared to the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
70% compared to the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
3.3% compared to the activity with catechol
-
-
?
4-chlorocatechol + O2
(2E,4Z)-3-chlorohexa-2,4-dienedioate
70% compared to the activity with catechol
-
-
?
4-chlorocatechol + O2
4-chloro-cis,cis-muconate
28.05% of the activity compared to catechol
-
-
?
4-chlorocatechol + O2
4-chloro-cis,cis-muconate
28.05% of the activity compared to catechol
-
-
?
4-chlorocatechol + O2
4-chloro-cis,cis-muconate
-
-
-
-
?
4-chlorocatechol + O2
?
-
-
-
-
?
4-chlorocatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
4-chlorocatechol + O2
?
-
-
-
-
?
4-chlorocatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
4-chlorocatechol + O2
?
-
-
-
-
?
4-chlorocatechol + O2
?
-
-
-
-
?
4-fluorocatechol + O2
3-fluoro-cis,cis-muconate
-
-
-
-
?
4-fluorocatechol + O2
3-fluoro-cis,cis-muconate
-
-
-
-
?
4-fluorocatechol + O2
3-fluoro-cis,cis-muconate
-
-
-
-
?
4-hydroxybenzoic acid + O2
?
-
-
-
?
4-hydroxybenzoic acid + O2
?
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
better substrate than catechol
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
better substrate than catechol
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
poor substrate
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
poor substrate
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
free enzyme shows 1.5times the activity of immobilized enzyme
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
preferred substrate
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
-
-
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
136.4% compared to the activity with catechol
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
18.2% compared to the activity with catechol
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
18.2% compared to the activity with catechol
-
-
?
4-methylcatechol + O2
(2Z,4Z)-3-methylhexa-2,4-dienedioate
136.4% compared to the activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
CatA1: 39.5% of the activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
CatA2: 13.1% of the activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
CatA1: 39.5% of the activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
CatA2: 13.1% of the activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
-
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
-
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
-
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
43% of the activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
43% of the activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
76% of activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
76% of activity with catechol
-
-
?
4-methylcatechol + O2
3-methyl-cis,cis-muconate
-
enzyme from aniline-grown cells: 86% of the activity with catechol, enzyme from L-malate-grown cells: 87% of the activity with catechol
-
-
?
4-methylcatechol + O2
3-methylhexa-2,4-dienedioate
-
reaction catalyzed by catechol 1,2-dioxygenase type I and type II
-
-
?
4-methylcatechol + O2
3-methylhexa-2,4-dienedioate
-
reaction catalyzed by catechol 1,2-dioxygenase type I and type II
-
-
?
4-methylcatechol + O2
4-methyl-cis,cis-muconate
the enzyme preferentially recognizes 4-substituted over 3-substituted catechols
-
-
?
4-methylcatechol + O2
4-methyl-cis,cis-muconate
the enzyme preferentially recognizes 4-substituted over 3-substituted catechols
-
-
?
4-methylcatechol + O2
4-methyl-cis,cis-muconate
90.12% of the activity compared to catechol
-
-
?
4-methylcatechol + O2
4-methyl-cis,cis-muconate
90.12% of the activity compared to catechol
-
-
?
4-methylcatechol + O2
4-methyl-cis,cis-muconate
71.5% activity compared to catechol
-
-
?
4-methylcatechol + O2
4-methyl-cis,cis-muconate
23.0% of the activity with catechol
-
-
?
4-methylcatechol + O2
4-methyl-cis,cis-muconate
23.0% of the activity with catechol
-
-
?
4-methylcatechol + O2
?
-
-
-
-
?
4-methylcatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
4-methylcatechol + O2
?
-
-
-
-
?
4-methylcatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
4-methylcatechol + O2
?
-
61% activity compared to catechol
-
-
?
4-methylcatechol + O2
?
-
assay at 60°C, pH 7.0
-
-
?
4-methylcatechol + O2
?
-
assay at 60°C, pH 7.0
-
-
?
4-methylcatechol + O2
?
-
-
-
-
?
4-methylcatechol + O2
?
-
-
-
-
?
4-methylpyrocatechol + O2
2,4,5-trimethyl-cis-cis-muconate
-
-
-
-
?
4-methylpyrocatechol + O2
2,4,5-trimethyl-cis-cis-muconate
-
-
-
-
?
4-methylpyrocatechol + O2
2,4,5-trimethyl-cis-cis-muconate
-
-
-
-
?
4-methylpyrocatechol + O2
2,4,5-trimethyl-cis-cis-muconate
-
-
-
-
?
4-methylpyrocatechol + O2
2,4,5-trimethyl-cis-cis-muconate
-
-
-
-
?
4-tert-butylcatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
4-tert-butylcatechol + O2
?
assay at pH 8.0, 30°C
-
-
?
benzene-1,2,4-triol + O2
?
-
16% of the activity with catechol
-
-
?
benzene-1,2,4-triol + O2
?
-
16% of the activity with catechol
-
-
?
catechol + ?
?
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
best substrate
-
-
?
catechol + O2
cis,cis-muconate
best substrate
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
best substrate
-
-
?
catechol + O2
cis,cis-muconate
catechol binds to the Fe(III) as a dianion. Protonation of an endogenous tyrosinate ligand after it dissociates from the ferric center upon substrate binding
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
best substrate
-
-
?
catechol + O2
cis,cis-muconate
-
100% activity
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
ir
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
both catechol dioxygenases, CatA1 and CatA2 are produced in benzoate-grown cells, CatA1 is undetectable when strain TH2 is grown on 2-chlorobenzoate or cis,cis-muconate. Production of CatA1 during growth on 2-chlorobenzoate or cis,cis-muconate is observed when cat2 genes are disrupted. The inducer of Cat1 is benzoate. cis,cis-Muconate or its metabolite acts as an inducer for CatA2. Genes are not indispensable for growth of strain TH2 on 2-chlorobenzoate, they are advantageous
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
both catechol dioxygenases, CatA1 and CatA2 are produced in benzoate-grown cells, CatA1 is undetectable when strain TH2 is grown on 2-chlorobenzoate or cis,cis-muconate. Production of CatA1 during growth on 2-chlorobenzoate or cis,cis-muconate is observed when cat2 genes are disrupted. The inducer of Cat1 is benzoate. cis,cis-Muconate or its metabolite acts as an inducer for CatA2. Genes are not indispensable for growth of strain TH2 on 2-chlorobenzoate, they are advantageous
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
reaction catalyzed by catechol 1,2-dioxygenase type I
-
-
?
catechol + O2
cis,cis-muconate
-
reaction catalyzed by catechol 1,2-dioxygenase type I
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
intradiol dioxygenase reaction
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
catechol 1,2-dioxygenase activity is induced eightfold in cultures grown on salicylate compared to cultures grown on glucose
-
-
?
catechol + O2
cis,cis-muconate
-
catechol 1,2-dioxygenase activity is induced eightfold in cultures grown on salicylate compared to cultures grown on glucose
-
-
?
catechol + O2
cis,cis-muconate
-
intradiol, assay at 60°C, pH 7.0
-
-
?
catechol + O2
cis,cis-muconate
-
intradiol, assay at 60°C, pH 7.0
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
the enzyme is involved in the catabolic pathway of L-tryptophan degradation, overview
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
i.e. cis,cis-hexadienedioate or (2Z,4Z)-hexa-2,4-dienedioate
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
catechol is an intermediate of the indole-3-acetic acid catabolic pathway, overview
-
-
?
catechol + O2
cis,cis-muconate
-
isozyme1 is able to function as lyophilized enzyme in a non-aqueous environment catalyzing the oxidation of catechol in n-hexane, overview
-
-
?
catechol + O2
cis,cis-muconate
-
benzoate degadation pathway
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
100% activity
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
100% activity
-
-
?
catechol + O2
cis,cis-muconate
-
the enzyme is involved in the biodegradation of benzothiazole
-
-
?
catechol + O2
cis,cis-muconate
-
the enzyme is involved in the biodegradation of benzothiazole
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
best substrate
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
-
?
catechol + O2
cis,cis-muconate
-
-
-
?
catechol + O2
cis,cis-muconate
best substrate
-
-
?
catechol + O2
cis,cis-muconate
Stutzerimonas stutzeri
-
-
-
?
catechol + O2
cis,cis-muconate
Stutzerimonas stutzeri GOM2
-
-
-
?
catechol + O2
cis,cis-muconic acid
-
-
-
-
?
catechol + O2
cis,cis-muconic acid
-
-
-
?
catechol + O2
cis,cis-muconic acid
-
-
-
?
hydroxyquinol + O2
maleylacetic acid
-
-
-
-
?
hydroxyquinol + O2
maleylacetic acid
-
-
-
-
?
hydroxyquinol + O2
maleylacetic acid
-
better substrate than catechol
-
?
hydroxyquinol + O2
maleylacetic acid
-
better substrate than catechol
-
?
phenol + O2
?
best substrate
-
-
?
phenol + O2
?
best substrate
-
-
?
pyrocatechol + O2
2,5-dimethyl-cis-cis-muconate
-
-
-
-
?
pyrocatechol + O2
2,5-dimethyl-cis-cis-muconate
-
-
-
-
?
pyrocatechol + O2
2,5-dimethyl-cis-cis-muconate
-
-
-
-
?
pyrocatechol + O2
2,5-dimethyl-cis-cis-muconate
-
-
-
-
?
pyrocatechol + O2
2,5-dimethyl-cis-cis-muconate
-
-
-
-
?
pyrogallol + O2
?
-
-
-
-
?
pyrogallol + O2
?
-
-
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
poor substrate
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
poor substrate
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
180% of the activity with catechol
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
180% of the activity with catechol
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
-
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
-
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
i.e.benzene-1,2,3-triol
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
i.e.benzene-1,2,3-triol
-
-
?
pyrogallol + O2
alpha-hydroxymuconic acid
-
-
-
-
?
additional information
?
-
-
no substrates: 4-nitrocatechol, alpha-chloro-3,4-dihydroxyacetophenone, 3,4-dihydroxyphenylacetic acid, 3,4-dihydroxycinnamic acid, protocatechuic acid, protoacatechualdehyde, pyrogallol
-
-
?
additional information
?
-
-
no substrates: 4-nitrocatechol, alpha-chloro-3,4-dihydroxyacetophenone, 3,4-dihydroxyphenylacetic acid, 3,4-dihydroxycinnamic acid, protocatechuic acid, protoacatechualdehyde, pyrogallol
-
-
?
additional information
?
-
-
extradiol cleavage of 3-methylcatechol, no substrate: 3-chlorocatechol, protocatechuic acid
-
-
?
additional information
?
-
-
both intradiol and extradiol cleavage of 3-methylcatechol
-
-
?
additional information
?
-
-
poor or no activity with 3-methylcatechol, 4-methylcatechol, and 4-nitrocatechol
-
-
?
additional information
?
-
-
poor or no activity with 3-methylcatechol, 4-methylcatechol, and 4-nitrocatechol
-
-
?
additional information
?
-
-
intradiol cleavage of 3-and 4-methylcatechol, no extradiol cleavage of 3-methylcatechol or 3-chlorocatechol, slight intradiol cleavage activity for 3- and 4-substituted halocatechols, CD-II shows no activity for 4-chlorocatechol, no substrate: protocatechuic acid
-
-
?
additional information
?
-
-
inducible on benzamide, not on L-malate
-
-
?
additional information
?
-
-
intradiol cleavage of 3-and 4-methylcatechol, no extradiol cleavage of 3-methylcatechol or 3-chlorocatechol, slight intradiol cleavage activity for 3- and 4-substituted halocatechols, CD-II shows no activity for 4-chlorocatechol, no substrate: protocatechuic acid
-
-
?
additional information
?
-
-
inducible on benzamide, not on L-malate
-
-
?
additional information
?
-
-
no substrates: 3-methylcatechol, isopropylcatechol
-
-
?
additional information
?
-
CatA2: no activity with 3-chlorocatechol
-
-
?
additional information
?
-
CatA2: no activity with 3-chlorocatechol
-
-
?
additional information
?
-
CatA2: no activity with 3-chlorocatechol
-
-
?
additional information
?
-
CatA2: no activity with 3-chlorocatechol
-
-
?
additional information
?
-
-
ratios of intradiol to extradiol activity of CD I and CD II 1000:120 and 100:3 respectively
-
-
?
additional information
?
-
-
inducible on aniline, not on L-malate
-
-
?
additional information
?
-
-
ratios of intradiol to extradiol activity of CD I and CD II 1000:120 and 100:3 respectively
-
-
?
additional information
?
-
-
inducible on aniline, not on L-malate
-
-
?
additional information
?
-
-
the enzyme is involved in degradation of 4-chlorobenzenesulfonic acid, 4CBSA, the major polar by-product of the chemical synthesis of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl) ethane, DDT, overview, 4-chlorobenzenesulfonic acid catabolic pathway, overview
-
-
?
additional information
?
-
-
no activity with 4-sulfocatechol
-
-
?
additional information
?
-
-
no substrates: adrenolutine, p-aminocatechol, protocatechuic acid, 2,3-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, trans-5,6-dihydroxycyclohexadiene, pyrogallol, dopa, homogentisic acid, gentisic acid
-
-
?
additional information
?
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-
no substrates: adrenolutine, p-aminocatechol, protocatechuic acid, 2,3-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, trans-5,6-dihydroxycyclohexadiene, pyrogallol, dopa, homogentisic acid, gentisic acid
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
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-
both intradiol and extradiol cleavage activities toward 3-substituted catechols
-
-
?
additional information
?
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-
enzyme intermediates
-
-
?
additional information
?
-
-
no substrates: 4-nitrocatechol, protocatechuic acid, ratios of intradiol and extradiol cleavage activities for 3-methylcatechol and 3-methoxycatechol 22 : 4.3
-
-
?
additional information
?
-
-
catechol 1,2-dioxygenase is induced by benzoate
-
-
?
additional information
?
-
no activity with vanillic acid
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
both intradiol and extradiol cleavage activities toward 3-substituted catechols
-
-
?
additional information
?
-
-
catechol 1,2-dioxygenase is induced by benzoate
-
-
?
additional information
?
-
no activity with vanillic acid
-
-
?
additional information
?
-
no activity with 3-chlorocatechol
-
-
?
additional information
?
-
no activity with 3-chlorocatechol
-
-
?
additional information
?
-
-
extradiol cleavage in addition to intradiol fission at a ratio 1:14 with pyrocatechase I, not with pyrocatechase II
-
-
?
additional information
?
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-
extradiol cleavage in addition to intradiol fission at a ratio 1:14 with pyrocatechase I, not with pyrocatechase II
-
-
?
additional information
?
-
-
no intradiol cleavage of 3- and 4-chlorocatechol or 4-fluorocatechol, no substrates: protocatechuic acid
-
-
?
additional information
?
-
-
no intradiol cleavage of 3- and 4-chlorocatechol or 4-fluorocatechol, no substrates: protocatechuic acid
-
-
?
additional information
?
-
-
no substrates: 3,4-dihydroxybenzoate, 3-methoxy-4-hydroxybenzoate, 2,4-dihydroxybenzoate, 3,5-dihydroxybenzoate, 3,4,5-trihydroxybenzoate
-
-
?
additional information
?
-
-
no substrates: 3,4-dihydroxybenzoate, 3-methoxy-4-hydroxybenzoate, 2,4-dihydroxybenzoate, 3,5-dihydroxybenzoate, 3,4,5-trihydroxybenzoate
-
-
?
additional information
?
-
-
poor substrates: 4-chloropyrocatechol, 3-methoxypyrocatechol
-
-
?
additional information
?
-
-
intradiol cleavage of 3- and 4-methylcatechol, but not extradiol cleavage of 3-methylcatechol
-
-
?
additional information
?
-
-
inducible on aniline, not on L-malate
-
-
?
additional information
?
-
-
intradiol cleavage of 3- and 4-methylcatechol, but not extradiol cleavage of 3-methylcatechol
-
-
?
additional information
?
-
-
inducible on aniline, not on L-malate
-
-
?
additional information
?
-
the enzyme is involved in the aerobic biodegradation of chloroaromatic compounds
-
-
?
additional information
?
-
-
the enzyme is involved in the aerobic biodegradation of chloroaromatic compounds
-
-
?
additional information
?
-
the enzyme is involved in the aerobic biodegradation of chloroaromatic compounds
-
-
?
additional information
?
-
-
the enzyme is involved in the aerobic biodegradation of chloroaromatic compounds
-
-
?
additional information
?
-
-
poor substrates: 4-chloropyrocatechol, 3-methoxypyrocatechol
-
-
?
additional information
?
-
-
poor substrates: 4-chloropyrocatechol, 3-methoxypyrocatechol
-
-
?
additional information
?
-
-
poor substrates: 4-chloropyrocatechol, 3-methoxypyrocatechol
-
-
?
additional information
?
-
-
poor substrates: 4-chloropyrocatechol, 3-methoxypyrocatechol
-
-
?
additional information
?
-
-
synthesized constitutively. When the bacterium is incubated on a medium with D-glucose, L-malate, isoleucine, leucine, etc., it synthesizes more catechol 1,2-dioxygenase than that in cells grown on aniline
-
-
?
additional information
?
-
-
strain KB2 degrades 13 mM 3,4-dihydroxybenzoate, 10 mM benzoic acid and 12 mM phenol within 24 h of incubation
-
-
?
additional information
?
-
substrate specificity, overview. No activity with 3-chlorocatechol, 4-chlorocatechol, 3,5-dichlorocatechol, 4,5-dichlorocatechol, and hydroquinone
-
-
?
additional information
?
-
-
substrate specificity, overview. No activity with 3-chlorocatechol, 4-chlorocatechol, 3,5-dichlorocatechol, 4,5-dichlorocatechol, and hydroquinone
-
-
?
additional information
?
-
-
strain KB2 degrades 13 mM 3,4-dihydroxybenzoate, 10 mM benzoic acid and 12 mM phenol within 24 h of incubation
-
-
?
additional information
?
-
substrate specificity, overview. No activity with 3-chlorocatechol, 4-chlorocatechol, 3,5-dichlorocatechol, 4,5-dichlorocatechol, and hydroquinone
-
-
?