1.13.11.12: linoleate 13S-lipoxygenase

This is an abbreviated version!
For detailed information about linoleate 13S-lipoxygenase, go to the full flat file.

Word Map on EC 1.13.11.12

1.13.11.12

arachidonic

cyclooxygenase

leukotriene

prostaglandin

indomethacin

linoleic

nordihydroguaiaretic

eicosanoids

phospholipase

platelet

thromboxane

hydroperoxide

leukocyte

polyunsaturated

phospholipid

ndga

hetes

neutrophil

artery

12-hete

ionophore

polymorphonuclear

lipoxins

radioimmunoassay

paf

cox-2

oxylipins

prostacyclin

jasmonic

docosahexaenoic

eicosapentaenoic

histamine

aspirin

platelet-activating

epoxyeicosatrienoic

bronchoconstriction

endoperoxide

quinacrine

6-keto-pgf1

6-keto-prostaglandin

medicine

food industry

synthesis

prostanoids

aa-induced

baicalein

piroxicam

mepacrine

vasoconstriction

epoxygenase

ibuprofen

meclofenamate

zymosan

biotechnology

Reaction

(9Z,11E,13S,15Z)-13-hydroperoxyoctadeca-9,11,15-trienoate

Synonyms

(13S)-lipoxygenase, 13-lipoxygenase, 13-LOX, 13S-lipoxygenase, 15-lipoxygenase-1, 15-LOX-1, 9/13-LOX, acidic lipoxygenase, Alox15, arachidonic acid 15S-lipoxygenating enzyme, AtLOX-2, AtLOX-3, AtLOX-4, AtLOX-6, CmLOX10, CmLOX13, iron 13S-lipoxygenase, liipoxygenase, linoleate 13-lipoxygenase, linoleate 13S-lipoxygenase, linoleate oxygen oxidoreductase, linoleate: oxygen oxidoreductase, linoleate:oxygen oxidoreductase, lipoxygenase, lipoxygenase 2, lipoxygenase-1, lipoxygenase-2, lipoxygenase-3, lipoxygenase-4, lipoxygenase-6, LO-1, LOX, LOX-1, LOX-2, LOX1, LOX10, LOX11, LOX12, LOX2, LOX2:Hv:1, LOX2:Md:2b, LOX2b, LOX3, LOX4, LOX6, LOX7, LOX8, LOX9, LoxA, Lpx-A2, MSD2, Oep1LOX2, Oep2LOX2, omega-6 linoleate lipoxygenase, PA-LOX, RCI-1, SBLO-1, secreted lipoxygenase, SLO, soybean lipoxygenase-1, StLOX2, StLOX3, type-1 LOX, type-2 13-LOX

ECTree

1 Oxidoreductases

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.11 With incorporation of two atoms of oxygen

1.13.11.12 linoleate 13S-lipoxygenase

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Results	in table
2	Activating Compound
107	AA Sequence
15	Application
1	CAS Registry Number
30	Cloned(Commentary)
1	Crystallization (Commentary)
3835	Disease/ Diagnostics
18	Expression
35	General Information
109	IC50 Value
175	Inhibitors
18	kcat/KM [mM/s]
23	Ki Value [mM]
63	KM Value [mM]
20	Localization
32	Metals/Ions
15	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
85	Organism
9	Pathway
44	PDB ID
27	pH Optimum
16	pH Range
2	pH Stability
6	pI Value
6	Protein Variants
21	Purification (Commentary)
3	Reaction
3	Reaction Type
69	Reference
51	Source Tissue
14	Specific Activity [micromol/min/mg]
1	Storage Stability
147	Substrates and Products (Substrate)
28	Subunits
155	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
17	Temperature Range [°C]
4	Temperature Stability [°C]
23	Turnover Number [1/s]

KI Value

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KI Value on EC 1.13.11.12 - linoleate 13S-lipoxygenase

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0.022

11-thialinoleic acid

Glycine max

706032

0.035

14-thialinoleic acid

Glycine max

706032

0.0096

2-dodecyl-6-hydroxybenzoic acid

Glycine max

pH 9.0

706929

0.0028

2-hydroxy-6-[(8E)-pentadec-8-en-1-yl]benzoic acid

Glycine max

pH 9.0

706929

0.0064

6-pentadecanylsalicylic acid

Glycine max

pH 9.0

706929

1.1

alpha-tocopherol

Glycine max

704118

3.4

apigenin

Glycine max

704118

13.6

catechin

Glycine max

704118

10.7

ferulic acid

Glycine max

704118

6.7

gallic acid

L-ascorbic acid

0.0084 - 0.015

lauric acid

4 entries

0.0005 - 0.0009

lauroylethanolamide

4 entries

0.00409

nordihydroguaiaretic acid

Olea europaea

B6D1W5

pH 6.0, 25°C

702431

0.00188

propyl gallate

Olea europaea

B6D1W5

pH 6.0, 25°C

702431

1.7

resveratrol

Trolox