1.13.11.3: protocatechuate 3,4-dioxygenase
This is an abbreviated version!
For detailed information about protocatechuate 3,4-dioxygenase, go to the full flat file.
Word Map on EC 1.13.11.3
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1.13.11.3
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catecholate
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1,2-dioxygenase
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intradiol
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4-hydroxybenzoate
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3,4-dihydroxybenzoate
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beta-ketoadipate
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ring-cleavage
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gentisate
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beta-carboxy-cis,cis-muconate
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enol-lactone
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hydroxyquinol
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orville
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lipscomb
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fuscum
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cis-muconate
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4-methylcatechols
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3,5-di-tert-butylcatechol
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analysis
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environmental protection
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degradation
- 1.13.11.3
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catecholate
-
1,2-dioxygenase
-
intradiol
- 4-hydroxybenzoate
- 3,4-dihydroxybenzoate
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beta-ketoadipate
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ring-cleavage
- gentisate
- beta-carboxy-cis,cis-muconate
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enol-lactone
- hydroxyquinol
-
orville
-
lipscomb
- fuscum
-
cis-muconate
- 4-methylcatechols
- 3,5-di-tert-butylcatechol
- analysis
- environmental protection
- degradation
Reaction
Synonyms
3,4-PCase, 3,4-PCD, 3,4-PCDase, 3,4-POD, EC 1.13.1.3, EC 1.99.2.3, More, oxygenase, protocatechuate 3,4-di-, P3,4DO, P3,4O enzyme, P34O, PCA 3,4-dioxygenase, PcaG, PcaH, PcaHG, PCD, protocatchetuate 3,4-dioxygenase, protocatechuate 3,4-dioxygenase, protocatechuate oxygenase, protocatechuic 3,4-dioxygenase, protocatechuic 3,4-oxygenase, protocatechuic acid oxidase
ECTree
1.13.11.3 protocatechuate 3,4-dioxygenaseAdvanced search results
results (
results (Inhibitors
Inhibitors on EC 1.13.11.3 - protocatechuate 3,4-dioxygenase
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
(2E)-3-(3,4-dimethoxyphenyl)-N-hydroxyprop-2-enamide
over 90% inhibition at 0.2 mM
(2E)-N-hydroxy-3-(4-methoxyphenyl)prop-2-enamide
over 90% inhibition at 0.2 mM
1,10-phenanthroline
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0.005 mM, approx. 50% inhibition after 30 min, complete inhibition after 60 min, complete restoration of inactivated enzyme by addition of excess ferric EDTA complex
2-(2H-1,3-benzodioxol-5-yl)-N-[(4-fluorophenyl)methyl]-N-hydroxyacetamide
60% inhibition at 0.2 mM
3-(3,4-dimethoxyphenyl)-N-hydroxy-N-octylpropanamide
57% inhibition at 0.2 mM
3-(3,4-dimethoxyphenyl)-N-hydroxypropanamide
60% inhibition at 0.2 mM
2,2'-dipyridyl
activates the enzyme immobilized on calcium alginate, but inhibits the free enzyme and the enzyme immobilized on glyoxyl agarose, at 0.3 mM
2-Hydroxyisonicotinic acid N-oxide
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0.000025 mM, 50% inactivation after 10 min, most potent inhibitor
Al3+
slight inhibition of the glyoxyl agarose-immobilized enzyme
butanol
inhibits the activity of the enzyme immobilized on glyoxyl agarose by 23.5% at 0.3 mM
EDTA
activates the enzyme immobilized on calcium alginate, but inhibits the free enzyme and the enzyme immobilized on glyoxyl agarose, at 0.3 mM
ethanol
inhibits the activity of the enzyme immobilized on glyoxyl agarose by 50% at 0.3 mM
Fe3+
inhibits the free enzyme and the enzyme immobilized on glyoxyl agarose
methanol
inhibits the activity of the enzyme immobilized on calcium alginate by 28% at 0.3 mM
Propanol
inhibits the activity of the enzyme immobilized on glyoxyl agarose by 23% at 0.3 mM
additional information
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not inhibited by iodoacetamide, 5,5'-dithiobis(2-nitrobenzoate), mercaptoethanol, dithiothreitol, glutathione, o-phenanthroline and H2O2
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additional information
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not inhibited by arsenate, iodoacetate, semicarbazide, N-phenylmaleimide, fluoride or cyanide
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additional information
poor inhibition by N-hydroxy-3-(4-methoxyphenyl)propanamide at 0.2 mM
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additional information
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poor inhibition by N-hydroxy-3-(4-methoxyphenyl)propanamide at 0.2 mM
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additional information
protective effect of immobilization on calcium alginate on enzyme activity is observed in the presence of Cd2+, Al3+, and Fe3+ while in the presence of Mn2+ and Zn2+ the inhibitory effect of metals on enzyme activity increases
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additional information
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protective effect of immobilization on calcium alginate on enzyme activity is observed in the presence of Cd2+, Al3+, and Fe3+ while in the presence of Mn2+ and Zn2+ the inhibitory effect of metals on enzyme activity increases
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