1.13.11.72: 2-hydroxyethylphosphonate dioxygenase

This is an abbreviated version!
For detailed information about 2-hydroxyethylphosphonate dioxygenase, go to the full flat file.

Reaction

Synonyms

HEPD, hydroxyethylphosphonate dioxygenase, PhdP, phpD

ECTree

     1 Oxidoreductases

         1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

             1.13.11 With incorporation of two atoms of oxygen

                1.13.11.72 2-hydroxyethylphosphonate dioxygenase

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5	AA Sequence
3	Cloned(Commentary)
1	Cofactor
3	Crystallization (Commentary)
8	General Information
1	Inhibitors
6	kcat/KM [mM/s]
8	KM Value [mM]
6	Metals/Ions
9	Natural Substrates/ Products (Substrates)
27	Organism
4	Pathway
1	PDB ID
10	Protein Variants
2	Purification (Commentary)
7	Reaction
15	Reference
30	Substrates and Products (Substrate)
2	Subunits
14	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 1.13.11.72 - 2-hydroxyethylphosphonate dioxygenase

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SYSTEMATIC NAME

IUBMB Comments

2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming)

Requires non-heme-Fe(II). Isolated from some bacteria including Streptomyces hygroscopicus and Streptomyces viridochromogenes. The pro-R hydrogen at C-2 of the ethyl group is retained by the formate ion. Any stereochemistry at C-1 of the ethyl group is lost. One atom from dioxygen is present in each product. Involved in phosphinothricin biosynthesis.