1.13.11.77: oleate 10S-lipoxygenase
This is an abbreviated version!
For detailed information about oleate 10S-lipoxygenase, go to the full flat file.
Word Map on EC 1.13.11.77
-
1.13.11.77
-
indoleamine
-
oleic
-
nostoc
-
aeruginosa
-
hydroperoxide
-
l-tryptophan
-
nicotinamide
-
cyclooxygenases
-
punctiforme
-
indole
-
2,3-dioxygenases
-
nad+
- 1.13.11.77
- indoleamine
-
oleic
- nostoc
- aeruginosa
- hydroperoxide
- l-tryptophan
- nicotinamide
-
cyclooxygenases
- punctiforme
- indole
-
2,3-dioxygenases
- nad+
Reaction
Synonyms
(10S)-dioxygenase, (10S)-DOX, 10-dioxygenase, 10S-dioxygenase, 10S-DOX, 10S-DOX-like lipoxygenase, heme dioxygenase, linoleate 10S-dioxygenase, linoleate 10S-DOX, linoleate heme 10S-dioxygenase, LOX, Np-diox, Npun_R5469, oleate heme 10S-dioxygenase
ECTree
1.13.11.77 oleate 10S-lipoxygenaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 1.13.11.77 - oleate 10S-lipoxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
alpha-linolenate + O2
(8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate
-
-
-
-
?
alpha-linolenate + O2
(8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate
-
-
-
?
alpha-linolenate + O2
(8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate
-
60.4% activity compared to linoleate
-
-
?
alpha-linolenate + O2
(8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate
-
60.4% activity compared to linoleate
-
-
?
linoleate + O2
(8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate
-
-
-
-
?
linoleate + O2
(8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate
-
-
-
?
linoleate + O2
(8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate
racemic substrate, absolute stereospecific reaction, only formation of 10S product
-
-
?
linoleate + O2
(8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate
-
100% activity
-
-
?
linoleate + O2
(8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate
-
100% activity
-
-
?
oleate + O2
(8E,10S)-10-hydroperoxyoctadeca-8-enoate
-
preferred substrate
-
-
?
oleate + O2
(8E,10S)-10-hydroperoxyoctadeca-8-enoate
-
46% activity compared to linoleate
-
-
?
oleate + O2
(8E,10S)-10-hydroperoxyoctadeca-8-enoate
-
46% activity compared to linoleate
-
-
?
palmitoleic acid + O2
(8E,10S)-10-hydroperoxy-hexadeca-8-enoate
-
-
-
-
?
palmitoleic acid + O2
(8E,10S)-10-hydroperoxy-hexadeca-8-enoate
-
-
-
-
?
palmitoleic acid + O2
(8E,10S)-10-hydroperoxy-hexadeca-8-enoate
-
-
-
-
?
additional information
?
-
enzyme Np-diox is best described as an oleate or linoleate dioxygenase, albeit with alpha-linolenic acid very competitive at low substrate concentrations
-
-
?
additional information
?
-
-
optimization of assay conditions, overview
-
-
?
additional information
?
-
racemic 1-octen-3-ol is formed in reaction of linoleate 10S-hydroperoxide with hematin or ferrous ions
-
-
?
additional information
?
-
-
the activity of the enzyme is highest in unsaturated fatty acids containing double bonds in position 9 (oleic, linoleic and linolenic acids), linoleic acid being preferred over linolenic and oleic acids
-
-
?
additional information
?
-
-
the activity of the enzyme is highest in unsaturated fatty acids containing double bonds in position 9 (oleic, linoleic and linolenic acids), linoleic acid being preferred over linolenic and oleic acids
-
-
?
