1.13.99.3: tryptophan 2'-dioxygenase
This is an abbreviated version!
For detailed information about tryptophan 2'-dioxygenase, go to the full flat file.
Word Map on EC 1.13.99.3
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1.13.99.3
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indole-3-acetic
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tryptamine
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pyrrolnitrin
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indole-3-acetamide
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2,4-diacetylphloroglucinol
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diastereoisomeric
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indole-3-carboxaldehyde
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3-substituted
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medicine
- 1.13.99.3
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indole-3-acetic
- tryptamine
- pyrrolnitrin
- indole-3-acetamide
- 2,4-diacetylphloroglucinol
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diastereoisomeric
- indole-3-carboxaldehyde
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3-substituted
- medicine
Reaction
Synonyms
indole-3-alkane alpha-hydroxylase, indolyl-3-alkane alpha-hydroxylase, oxidase, tryptophan side-chain alpha,beta-, oxidase, tryptophan side-chain alpha,beta-, II, tryptophan side chain oxidase, tryptophan side chain oxidase II, tryptophan side chain oxidase type I, tryptophan side-chain alpha,beta-oxidase, tryptophan side-chain oxidase, TSO, TSO I, TSO II, TSOII
ECTree
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Reaction
Reaction on EC 1.13.99.3 - tryptophan 2'-dioxygenase
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primary reaction is hydroxylation of the side chain carbon adjacent to the indole ring, decarboxylation (of tryptophan only) is secondary
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L-tryptophan + O2 = (indol-3-yl)glycolaldehyde + CO2 + NH3
model of mechanism
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L-tryptophan + O2 = (indol-3-yl)glycolaldehyde + CO2 + NH3
primary reaction is hydroxylation of the side chain carbon adjacent to the indole ring, decarboxylation (of tryptophan only) is secondary
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