1.14.11.16: peptide-aspartate beta-dioxygenase

This is an abbreviated version!
For detailed information about peptide-aspartate beta-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.16

1.14.11.16

prolyl

hydroxylases

oxygen-dependent

ankyrin

hif-alpha

oxygen-sensing

junctin

humbug

fih-dependent

fih-mediated

alpha-ketoglutarate-dependent

junctate

medicine

analysis

Reaction

Synonyms

AAH, asparaginyl hydroxylase factor inhibiting HIF-1, aspartate beta-hydroxylase, aspartate-beta-hydroxylase, aspartate/asparagine-beta-hydroxylase, aspartyl (asparaginyl) beta-hydroxylase, aspartyl (asparaginyl)-beta-hydroxylase, aspartyl beta-hydroxylase, aspartyl-(asparaginyl) beta-hydroxylase, aspartyl-(asparaginyl)-b-hydroxylase, aspartyl-(asparaginyl)-beta-hydroxylase, aspartyl-(asparagyl)-beta-hydroxylase, aspartyl-asparaginyl-beta-hydroxylase, aspartyl/asparaginyl beta-hydroxylase, aspartylpeptide beta-dioxygenase, ASPH, EGF beta-hydroxylase, EGFH, factor inhibiting HIF, factor inhibiting hypoxia-inducible factor, factor inhibiting hypoxia-inducible transcription factor (HIF), factor-inhibiting hypoxia-inducible factor, FIH, HAAH, HIF asparaginyl hydroxylase, human aspartyl (asparaginyl) beta-hydroxylase, hypoxia-inducible factor asparaginyl hydroxylase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

1.14.11.16 peptide-aspartate beta-dioxygenase

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Results	in table
2	Activating Compound
235	AA Sequence
7	Application
1	CAS Registry Number
18	Cloned(Commentary)
4	Crystallization (Commentary)
162	Disease/ Diagnostics
13	Expression
24	General Information
77	IC50 Value
87	Inhibitors
4	kcat/KM [mM/s]
25	KM Value [mM]
12	Localization
14	Metals/Ions
10	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
49	Organism
45	PDB ID
2	pH Optimum
1	pH Range
1	Posttranslational Modification
18	Protein Variants
14	Purification (Commentary)
1	Reaction
7	Reaction Type
49	Reference
61	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
48	Substrates and Products (Substrate)
3	Subunits
65	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
8	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.14.11.16 - peptide-aspartate beta-dioxygenase

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(1S,2S,4R)-3-oxalobicyclo[2.2.1]hept-5-ene-2-carboxylic acid