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1.14.11.20: deacetoxyvindoline 4-hydroxylase

This is an abbreviated version!
For detailed information about deacetoxyvindoline 4-hydroxylase, go to the full flat file.

Word Map on EC 1.14.11.20

Reaction

deacetoxyvindoline
+
2-oxoglutarate
+
O2
=
deacetylvindoline
+
succinate
+
CO2

Synonyms

D4H, deacetoxyvindoline 4-hydroxylase, desacetoxyvindoline 4-hydroxylase, desacetoxyvindoline-4-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.20 deacetoxyvindoline 4-hydroxylase

Substrates Products

Substrates Products on EC 1.14.11.20 - deacetoxyvindoline 4-hydroxylase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
deacetoxyvindoline + 2-oxoglutarate + O2
deacetylvindoline + succinate + CO2
show the reaction diagram
desacetoxyvindoline + 2-oxoglutarate + O2
desacetylvindoline + succinate + CO2
show the reaction diagram
-
strictly specific for position 4, no hydroxylation of indole alkaloid substrates with a 2,3-double bond
-
?
additional information
?
-
-
the desacetoxyvindoline-4-hydroxylase interacts with the deacetylvindoline-4-O-acetyltransferase, analysis via yeast two-hybrid system
-
-
?