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1.14.11.21: clavaminate synthase

This is an abbreviated version!
For detailed information about clavaminate synthase, go to the full flat file.

Word Map on EC 1.14.11.21

Reaction

deoxyamidinoproclavaminate
+
2-oxoglutarate
+
O2
=
amidinoproclavaminate
+
succinate
+
CO2

Synonyms

CAS, CAS1, CAS2, clavaminate synthase 1, clavaminate synthase 2, clavaminic acid synthase, CS, synthase, clavaminate

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.21 clavaminate synthase

Natural Substrates Products

Natural Substrates Products on EC 1.14.11.21 - clavaminate synthase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(3S,5S)-dihydroclavaminate + 2-oxoglutarate + O2
(3S,5S)-clavaminate + succinate + CO2 + H2O
show the reaction diagram
the enzyme is involved in clavulanic acid biosynthesis
-
-
?
deoxyamidinoproclavaminate + 2-oxoglutarate + O2
amidinoproclavaminate + succinate + CO2 + H2O
show the reaction diagram
deoxyguanidinoproclavaminate + 2-oxoglutarate + O2
guanidinoproclavaminate + succinate + CO2 + H2O
show the reaction diagram
dihydroclavaminate + 2-oxoglutarate + O2
clavaminate + succinate + CO2 + H2O
show the reaction diagram
proclavaminate + 2-oxoglutarate + O2
dihydroclavaminate + succinate + CO2 + H2O
show the reaction diagram
additional information
?
-