1.14.11.3: pyrimidine-deoxynucleoside 2'-dioxygenase

This is an abbreviated version!
For detailed information about pyrimidine-deoxynucleoside 2'-dioxygenase, go to the full flat file.

Reaction

Synonyms

deoxyuridine 2'-dioxygenase, deoxyuridine 2'-hydroxylase, JBP1, JBP2, pyrimidine deoxyribonucleoside 2'-hydroxylase, thymidine 2'-dioxygenase, thymidine 2'-hydroxylase, thymidine 2-oxoglutarate dioxygenase, thymidine dioxygenase

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

                1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase

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Results	in table
12	Activating Compound
1	CAS Registry Number
1	Cloned(Commentary)
25	General Information
23	Inhibitors
8	KM Value [mM]
9	Metals/Ions
4	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
53	Organism
5	pH Optimum
5	Protein Variants
4	Purification (Commentary)
1	Reaction
4	Reaction Type
18	Reference
4	Source Tissue
3	Specific Activity [micromol/min/mg]
29	Substrates and Products (Substrate)
2	Subunits
17	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

KM Value

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KM Value on EC 1.14.11.3 - pyrimidine-deoxynucleoside 2'-dioxygenase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.19

2'-deoxyuridine

Neurospora crassa

-

-

439174

0.3

2-oxoglutarate

Neurospora crassa

-

-

439174

0.15

5-bromodeoxyuridine

Neurospora crassa

-

-

439174

0.29

5-Hydroxymethyldeoxyuridine

Neurospora crassa

-

-

439174

0.29

6-Azathymidine

Neurospora crassa

-

-

439174

0.45

Fe2+

Neurospora crassa

-

at pH 7.2 in 50 mM phosphate buffer

439174

0.09

thymidine

Neurospora crassa

-

-

439174

0.07

thymidylate

Neurospora crassa

-

-

439174