1.14.11.4: procollagen-lysine 5-dioxygenase

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For detailed information about procollagen-lysine 5-dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.4

1.14.11.4

prolyl

ehlers-danlos

hydroxylysine

jumonji

fibrosis

procollagens

fragility

domain-containing

hydroxylases

osteogenesis

4-hydroxylase

kyphoscoliosis

imperfecta

demethylase

glucosyltransferase

pyridinoline

hypermobl

galactosyltransferase

contractures

minoxidil

hypotonia

hydroxylysyl

hypermobility

bruck

fkbp10

hyperelasticity

underhydroxylated

sclera

scoliosis

laxity

chick-embryo

hyperextensibility

2-oxoglutarate-dependent

serpinh1

galactosylhydroxylysyl

ppib

medicine

crtap

diagnostics

Reaction

[procollagen]-(2S,5R)-5-hydroxy-L-lysine

Synonyms

2-oxoglutarate 5-dioxygenase 2, collagen lysine hydroxylase, Jmjd6, L230, LH, LH1, LH2, LH2 (long), LH2a, LH2b, LH3, LH3/PLOD3, lysine hydroxylase, lysine, 2-oxoglutarate 5-dioxygenase, lysine-2-oxoglutarate dioxygenase, lysyl 5S-hydroxylase, lysyl hydroxylase, lysyl hydroxylase 1, lysyl hydroxylase 2, lysyl hydroxylase 2 (long), lysyl hydroxylase 2a, lysyl hydroxylase 2b, lysyl hydroxylase 3, Lysyl hydroxylase-2b, lysyl-hydroxylase 1, lysylhydroxylase 2, lysylprotocollagen dioxygenase, More, multifunctional collagen lysyl hydroxylase, oxygenase, protocollagen lysine, di-, peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase, peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase, PLOD, Plod1, PLOD2, Plod2a, Plod2b, PLOD2iso1, PLOD2iso2, PLOD3, procollagen lysyl hydroxylase 2, procollagen-lysine, procollagen-lysine 2-oxoglutarate 5-dioxygenase, procollagen-lysine 2-oxoglutarate 5-dioxygenase 2, procollagen-lysine, 2-oxoglutarate 5-dioxygenase, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2, procollagen-lysine,2-oxoglutarate 5-dioxygenase, protocollagen lysine hydroxylase, protocollagen lysyl hydroxylase, telopeptide lysyl hydroxylase, TLH

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

1.14.11.4 procollagen-lysine 5-dioxygenase

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Results	in table
23	Activating Compound
3001	AA Sequence
7	Application
1	CAS Registry Number
47	Cloned(Commentary)
10	Cofactor
2	Crystallization (Commentary)
1234	Disease/ Diagnostics
13	Expression
64	General Information
11	General Stability
41	Inhibitors
2	kcat/KM [mM/s]
3	Ki Value [mM]
46	KM Value [mM]
36	Localization
22	Metals/Ions
25	Molecular Weight [Da]
68	Natural Substrates/ Products (Substrates)
240	Organism
3	Pathway
17	PDB ID
8	pH Optimum
3	pI Value
15	Posttranslational Modification
58	Protein Variants
20	Purification (Commentary)
3	Reaction
7	Reaction Type
88	Reference
180	Source Tissue
11	Specific Activity [micromol/min/mg]
5	Storage Stability
148	Substrates and Products (Substrate)
17	Subunits
180	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
5	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.14.11.4 - procollagen-lysine 5-dioxygenase

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2-oxoglutarate

Homo sapiens

O00469

competitive substrate inhibition

744168

Adrenochrome