1.14.11.43: (S)-dichlorprop dioxygenase (2-oxoglutarate)
This is an abbreviated version!
For detailed information about (S)-dichlorprop dioxygenase (2-oxoglutarate), go to the full flat file.
Reaction
Synonyms
(S)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-oxoglutarate-dependent (S)-dichlorprop dioxygenase, alpha-ketoglutarate-dependent (S)-dichlorprop dioxygenase, SdpA
ECTree
Advanced search results
Engineering
Engineering on EC 1.14.11.43 - (S)-dichlorprop dioxygenase (2-oxoglutarate)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
E69A
exhibits 30.8% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate. kcat/Km is 42% compared to the wild-type value
G97I/N98G
exhibits 3.8% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate. kcat/Km is 0.6% compared to the wild-type value
G97N/N98G
exhibits 0.3% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate
H208A
exhibits about 1.4% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate. kcat/Km is 0.1% compared to the wild-type value
H272A
exhibits about 1.2% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate
Q162F
exhibits about 4.8% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate
R207A
exhibits about 17.3% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate. kcat/Km is 2% compared to the wild-type value
R207V
exhibits about 2.8% of wild-type enzyme activity with (S)-2-(4-chloro-2-methylphenoxy)propanoate