1.14.11.49: uridine-5'-phosphate dioxygenase
This is an abbreviated version!
For detailed information about uridine-5'-phosphate dioxygenase, go to the full flat file.
Word Map on EC 1.14.11.49
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1.14.11.49
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huntington
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chorionic
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estriol
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somatomammotropin
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high-content
- 1.14.11.49
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huntington
-
chorionic
- estriol
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somatomammotropin
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high-content
Reaction
Synonyms
alpha-ketoglutarate:UMP dioxygenase, alpha-KG:UMP dioxygenase, LIPL, UMP:alpha-ketoglutarate dioxygenase, uridine-5-monophosphate alpha-ketoglutarate dioxygenase
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Substrates Products
Substrates Products on EC 1.14.11.49 - uridine-5'-phosphate dioxygenase
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REACTION DIAGRAM
5'-dehydrouridine + succinate + CO2 + phosphate
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UMP + 2-oxoglutarate + O2
5'-dehydrouridine + succinate + CO2 + phosphate
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UMP + 2-oxoglutarate + O2
5'-dehydrouridine + succinate + CO2 + phosphate
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in the absence of the prime substrate UMP, the enzyme is able to catalyze oxidative decarboxylation of 2-oxoglutarate, although at a significantly reduced rate
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additional information
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uridine and UDP, pyruvate, 2-oxoadipate, 2-oxobutyrate, 2-oxovalerate, and oxaloacetate are not recognized as substrates. The enzyme is unable to catalyze dephosphorylation and aldehyde formation using the remaining canonical, monophosphorylated ribo- or deoxyribonucleotides
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additional information
?
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in the absence of the prime substrate UMP, the enzyme is able to catalyze oxidative decarboxylation of 2-oxoglutarate, although at a significantly reduced rate
-
-
?
additional information
?
-
-
uridine and UDP, pyruvate, 2-oxoadipate, 2-oxobutyrate, 2-oxovalerate, and oxaloacetate are not recognized as substrates. The enzyme is unable to catalyze dephosphorylation and aldehyde formation using the remaining canonical, monophosphorylated ribo- or deoxyribonucleotides
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-
?