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1.14.11.6: thymine dioxygenase

This is an abbreviated version!
For detailed information about thymine dioxygenase, go to the full flat file.

Word Map on EC 1.14.11.6

Reaction

thymine
+
2-oxoglutarate
 +
O2
=
5-Hydroxymethyluracil
 +
succinate
 +
CO2

Synonyms

5-hydroxy-methyluracil dioxygenase, 5-hydroxy-methyluracil oxygenase, EC 1.14.11.5, Fe2+/2-oxoglutarate dependent hydroxylase, J binding protein 1, J binding protein 2, J-binding protein 1, J-binding protein 2, JBP1, JBP2, More, T7H, thymidine hydroxylase, thymine 7-hydroxylase, thymine dioxygenase, thymine hydroxylase, thymine-7-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
                1.14.11.6 thymine dioxygenase

Substrates Products

Substrates Products on EC 1.14.11.6 - thymine dioxygenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-ethylthymine + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
-
-
-
?
1-ethyluracil + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
-
-
-
?
1-methylthymine + 2-oxoglutarate + O2
1-methyl-5-(hydroxymethyl)uracil + thymine + formaldehyde + succinate + CO2
show the reaction diagram
1-methyluracil + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
-
-
-
?
5,6-dihydrothymine + 2-oxoglutarate + O2
5,6-dihydro-5-(hydroxymethyl)uracil + succinate + CO2
show the reaction diagram
-
-
-
?
5,6-dihydroxythymine + 2-oxoglutarate + O2
5,6-dihydro-5-(hydroxymethyl)uracil + succinate + CO2
show the reaction diagram
-
-
-
-
r
5-(2-hydroxyethyl)uracil + 2-oxoglutarate + O2
5-(1,2-dihydroxyethyl)uracil + succinate + CO2
show the reaction diagram
5-(methylthio)uracil + 2-oxoglutarate + O2
5-(methylsulfonyl)uracil + 5-(methylsulfinyl)uracil + succinate + CO2
show the reaction diagram
-
-
-
?
5-aminouracil + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
5-bromo-1-methyluracil + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
-
-
-
?
5-carboxyluracil + O2
?
show the reaction diagram
-
-
-
?
5-ethynyluracil + 2-oxoglutarate + O2 + H2O
5-(carboxymethyl)uracil + succinate + CO2
show the reaction diagram
5-fluorouracil + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
5-formyluracil + 2-oxoglutarate + O2
5-carboxyuracil + succinate + CO2
show the reaction diagram
5-formyluracil + O2
?
show the reaction diagram
-
-
-
?
5-hydroxymethyluracil + 2-oxoglutarate + O2
5-formyluracil + succinate + CO2
show the reaction diagram
5-hydroxyuracil + O2
?
show the reaction diagram
-
-
-
?
5-methylcytosine + 2-oxoglutarate + O2
?
show the reaction diagram
-
-
-
-
?
5-vinyluracil + 2-oxoglutarate + O2
5-(1,2-dihydroxyethyl)uracil + succinate + CO2
show the reaction diagram
6-azathymine + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
-
-
-
?
N1-methylthymine + 2-oxoglutarate + O2
N1-methyl-5-hydroxymethyluracil + succinate + CO2
show the reaction diagram
-
-
-
?
N1-methyluracil + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
-
-
-
?
thymine + 2-oxoglutarate + 2 O2
uracil-5-carboxylate + succinate + CO2 + H2O
show the reaction diagram
thymine + 2-oxoglutarate + O2
5-hydroxymethyluracil + succinate + CO2
show the reaction diagram
uracil + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
additional information
?
-