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1.14.12.1: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

This is an abbreviated version!
For detailed information about anthranilate 1,2-dioxygenase (deaminating, decarboxylating), go to the full flat file.

Word Map on EC 1.14.12.1

Reaction

anthranilate
+
NAD(P)H
+
H+
+
O2
=
catechol
+
CO2
+
NAD(P)+
+
NH3

Synonyms

AntDO, anthranilate hydroxylase, anthranilic acid hydroxylase, anthranilic hydroxylase, two-component anthranilate 1,2-dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

Engineering

Engineering on EC 1.14.12.1 - anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D218A
-
no activity
D218E
-
no activity
D218N
-
no activity
D218A
-
no activity
-
D218E
-
no activity
-
D218N
-
no activity
-