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1.14.12.12: naphthalene 1,2-dioxygenase

This is an abbreviated version!
For detailed information about naphthalene 1,2-dioxygenase, go to the full flat file.

Word Map on EC 1.14.12.12

Reaction

Naphthalene
+
NADH
 +
H+
 +
O2
=
(1R,2S)-1,2-dihydronaphthalene-1,2-diol
 +
NAD+

Synonyms

NAG, NAHA, nahAc, naphthalene 1,2-dioxygenase, naphthalene dioxygenase, naphthalene oxygenase, NDO, oxygenase, naphthalene di-

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                1.14.12.12 naphthalene 1,2-dioxygenase

Inhibitors

Inhibitors on EC 1.14.12.12 - naphthalene 1,2-dioxygenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
-
10 mM, 63% inhibition of ferredoxinNAP reductase
4-chloromercuribenzoate
-
0.0005 mM, 94% inhibition of ferredoxinNAP reductase
H2O2
-
0.4 mM, complete inactivation of reduced terminal dioxygenase ISPNAP after 10 min in the absence of ferrous iron
iodoacetate
-
10 mM, 50% inhibition of ferredoxinNAP reductase
N-ethylmaleimide
-
2 mM, 30% inhibition of ferredoxinNAP reductase
NaN3
-
40 mM, 46% inhibition of ferredoxinNAP reductase