1.14.13.1: salicylate 1-monooxygenase

This is an abbreviated version!
For detailed information about salicylate 1-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.1

1.14.13.1

catechol

naphthalene

1,2-dioxygenase

gentisate

sa-mediated

naphthalene-degrading

sa-deficient

sa-independent

analysis

diagnostics

Reaction

Synonyms

Efe-shyA, FAD/NADH-dependent SA 1-hydroxylase, FAD_binding_3 domain-containing protein, FGSG_03657, FgShy1, FgShyC, flavin-dependent monooxygenase salicylate hydroxylase, NahG, NahU, NRRL3_9723, oxygenase, salicylate 1-mono-, SA 1-decarboxylase/hydroxylase, SA 1-hydroxylase, SA hydroxylase, SA1H, SahA, salA, salcylic acid 1-hydroxylase, SALH, salicylate 1-hydroxylase, Salicylate 1-monooxygenase, salicylate hydroxylase, salicylate hydroxylase (decarboxylating), salicylate monooxygenase, salicylate, NADH: oxygen oxidoreductase, salicylate, NADH: oxygen oxidoreductase (1-hydroxylating, decarboxylating), salicylate-1-hydroxylase, salicylic acid hydroxylase, salicylic hydroxylase, SalOH, SHL, Shy1, ShyA, ShyC, SlSA 1H, SlSA1H, Solyc08g063130

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.1 salicylate 1-monooxygenase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
3	Activating Compound
1317	AA Sequence
5	Application
1	CAS Registry Number
16	Cloned(Commentary)
80	Cofactor
4	Crystallization (Commentary)
16	Expression
44	General Information
3	General Stability
22	Inhibitors
10	kcat/KM [mM/s]
4	Ki Value [mM]
62	KM Value [mM]
4	Localization
3	Metals/Ions
14	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
114	Organism
10	Pathway
10	PDB ID
12	pH Optimum
5	pH Range
1	pH Stability
17	Protein Variants
18	Purification (Commentary)
5	Reaction
4	Reaction Type
84	Reference
20	Source Tissue
37	Specific Activity [micromol/min/mg]
3	Storage Stability
226	Substrates and Products (Substrate)
18	Subunits
152	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
2	Temperature Range [°C]
5	Temperature Stability [°C]
10	Turnover Number [1/s]

Inhibitors

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Inhibitors on EC 1.14.13.1 - salicylate 1-monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Inhibitor Search

1,10-phenanthroline

Pseudomonas sp.

389999

1-hydroxy-2-naphthoate

Sphingomonas sp.

strong competitive inhibition of salicylate hydroxylation

ascorbic acid

slight

benzoate

competitive inhibitor

Br-

Cl-

CuSO4

F-

I-

Na2MoO4

slight

NO3-

inhibits biotransformation of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurzitane

657599

p-chloromercuribenzoate

SCN-

Trinitrobenzenesulfonic acid

Pseudomonas putida

irreversible inactivation, modification of a lysine residue results in loss of NADH-dehydrogenase activity suggesting its role in the NADH-binding site of the enzyme

390013

additional information

Pseudomonas putida

chemical modification of one arginine residue with glyoxal causes the enzyme to act as dehydrogenase, but not as oxygenase

390010