1.14.13.10: 2,6-dihydroxypyridine 3-monooxygenase

This is an abbreviated version!
For detailed information about 2,6-dihydroxypyridine 3-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.10

1.14.13.10

nicotine

duodenal

rickets

phosphorus

cabp

nicotinovorans

parathyroid

d-dependent

arthrobacter

calcium-binding

d-deficiency

Reaction

Synonyms

2,6-dihydroxypyridine hydroxylase, 2,6-dihydroxypyridine oxidase, 2,6-dihydroxypyridine-3-hydroxylase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.10 2,6-dihydroxypyridine 3-monooxygenase

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Results	in table
3	Activating Compound
35	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
6	Cofactor
1	Crystallization (Commentary)
1	General Stability
12	Inhibitors
1	KM Value [mM]
1	Localization
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
3	Organic Solvent Stability
7	Organism
3	Pathway
3	PDB ID
2	pH Optimum
1	pH Stability
1	Protein Variants
3	Purification (Commentary)
1	Reaction
4	Reaction Type
7	Reference
1	Renatured (Commentary)
2	Specific Activity [micromol/min/mg]
8	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
4	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 1.14.13.10 - 2,6-dihydroxypyridine 3-monooxygenase

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2,6-dihydroxypyridine + NADH + electron acceptor

2,3,6-trihydroxypyridine + NAD+ + reduced electron acceptor

Paenarthrobacter nicotinovorans

methylene blue and 2,6-dichlorophenol-indophenol can act as alternative electron acceptors

439040

2,6-dihydroxypyridine + NADH + O2

2,3,6-trihydroxypyridine + NAD+ + H2O

4 entries

additional information

Paenarthrobacter nicotinovorans

2-hydroxypyridine, 3-hydroxypyridine, 4-hydroxypyridine, 2,5-dihydroxypyridine, 2,6-dipicolinic acid, p-hydroxybenzoic acid, nicotinic acid and nicotine are no substrates for this enzyme

439040