1.14.13.101: senecionine N-oxygenase

This is an abbreviated version!
For detailed information about senecionine N-oxygenase, go to the full flat file.

Reaction

Synonyms

flavin-dependent monooxygenase, fmoa, GgPNO, oxygenase, senecionine N-, PA N-oxygenase, PNO, pyrrolizidine alkaloid N-oxygenase, senecionine monooxygenase (N-oxide-forming), senecionine N-oxygenase, SNO, TjSNO, ZvFMOa, ZvPNO

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.101 senecionine N-oxygenase

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Results	in table
3	Activating Compound
6	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
10	Cofactor
2	Crystallization (Commentary)
4	General Information
1	Inhibitors
5	kcat/KM [mM/s]
15	KM Value [mM]
3	Localization
4	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
16	Organism
3	Pathway
5	pH Optimum
1	pI Value
7	Protein Variants
5	Purification (Commentary)
1	Reaction
9	Reaction Type
15	Reference
13	Source Tissue
2	Specific Activity [micromol/min/mg]
78	Substrates and Products (Substrate)
4	Subunits
18	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.14.13.101 - senecionine N-oxygenase

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senecionine + NADPH + H+ + O2

senecionine N-oxide + NADP+ + H2O

2 entries

senecionine + NADPH + O2

senecionine N-oxide + NADP+ + H2O

Tyria jacobaeae

Q8MP06

706452

seneciphylline + NADPH + H+ + O2

seneciphylline N-oxide + NADP+ + H2O

Zonocerus variegatus

second best substrate

728567

additional information

2 entries