1.14.13.113: FAD-dependent urate hydroxylase

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For detailed information about FAD-dependent urate hydroxylase, go to the full flat file.

Reaction

Synonyms

FAD-dependent urate oxidase, flavin adenine dinucleotide-dependent urate oxidase, HpxO, HpxO enzyme, HpyO, urate hydroxylase, XCC0279

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.113 FAD-dependent urate hydroxylase

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Results	in table
471	AA Sequence
4	Cloned(Commentary)
8	Cofactor
2	Crystallization (Commentary)
13	kcat/KM [mM/s]
14	KM Value [mM]
3	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
6	Organism
4	Pathway
1	pH Optimum
8	Protein Variants
2	Purification (Commentary)
1	Reaction
1	Reaction Type
6	Reference
9	Substrates and Products (Substrate)
4	Subunits
12	Synonyms
1	Systematic Name
13	Turnover Number [1/s]

Reaction

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Reaction on EC 1.14.13.113 - FAD-dependent urate hydroxylase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

urate + NADH + H+ + O2 = 5-hydroxyisourate + NAD+ + H2O

a flavoprotein. The product 5-hydroxyisourate is spontaneously converted to allantoin

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