1.14.13.114: 6-hydroxynicotinate 3-monooxygenase
This is an abbreviated version!
For detailed information about 6-hydroxynicotinate 3-monooxygenase, go to the full flat file.
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Synonyms
6-hydroxynicotinic acid 3-monooxygenase, 6HNA monooxygenase, BB1770, BbNicC, NicC, PpNicC
ECTree
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Cofactor
Cofactor on EC 1.14.13.114 - 6-hydroxynicotinate 3-monooxygenase
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additional information
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riboflavin or FMN do not serve as enzyme cofactors
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FAD
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the enzyme activity is NADH-dependent and FAD-dependent. The holoenzyme contains 1 M of FAD per 1 M of enzyme. FAD gradually dissociates from the enzyme during purification. Without FAD, no pure enzyme activity is observed, but after the addition of FAD, the apoenzyme is activated immediately
NADH
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the enzyme activity is NADH-dependent and FAD-dependent. NADH is 5times more effective than NADPH